RES Structure and Function of the Fishes

  • Larry J. Mc Cumber
  • M. Michael Sigel
  • Richard J. Trauger
  • Marvin A. Cuchens


Fish are the earliest vertebrates which have a well-developed immune system characterized by both cellular and humoral branches endowed with specificity and memory. More specifically, since invertebrates apparently lack a molecule resembling the vertebrate antibody molecule (Bang, 1973; Shapiro, 1975), fish are the first group of animals which clearly possess an immunoglobulin component. In addition, although there is evidence indicating cellular function in recognition of non-self in invertebrates (reviewed in Cooper, 1976), again fish are the first group of animals where T-like and B-like lymphocytes may actually attain a level of specialization.


Rainbow Trout Effector Cell Allograft Rejection Bony Fish Cartilaginous Fish 
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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Larry J. Mc Cumber
    • 1
  • M. Michael Sigel
    • 1
  • Richard J. Trauger
    • 1
  • Marvin A. Cuchens
    • 2
  1. 1.Department of Microbiology and ImmunologyUniversity of South Carolina School of MedicineColumbiaUSA
  2. 2.Department of MicrobiologyUniversity of Mississippi Medical CenterJacksonUSA

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