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Messenger Ribonucleoprotein Particles

  • Chapter
Protein Biosynthesis in Eukaryotes

Part of the book series: NATO Advanced Study Institutes Series ((NSSA,volume 41))

Abstract

Messenger RNA, from the time of its synthesis in the nucleus through its translation and degradation, does not exist as free RNA in animal cells but rather always appear to be complexed with proteins. Free cytoplasmic ribonucleoprotein (RNP) particles containing non-ribosomal RNA were discovered by Spirin and coworkers (1) in 1964 and were called informosomes. Shortly thereafter, similar particles containing hnRNA were identified in cell nuclei (2). Both kinds of mRNP particles are heterogeneous in size and are rich in protein, with RNA/protein mass ratios of about 1:3. mRNPs have been found in all eukaryotic organisms examined.

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Authors and Affiliations

  1. Department of Biological Chemistry, School of Medicine, University of California, Davis, CA, 95616, USA

    John W. B. Hershey

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  1. John W. B. Hershey
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Editors and Affiliations

  1. The Institute for Virology, University of Rome, Rome, Italy

    R. Pérez-Bercoff

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© 1982 Plenum Press, New York

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Hershey, J.W.B. (1982). Messenger Ribonucleoprotein Particles. In: Pérez-Bercoff, R. (eds) Protein Biosynthesis in Eukaryotes. NATO Advanced Study Institutes Series, vol 41. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4124-6_6

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  • DOI: https://doi.org/10.1007/978-1-4684-4124-6_6

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4126-0

  • Online ISBN: 978-1-4684-4124-6

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