Advertisement

Peptide Chain Elongation and Termination in Eukaryotes

  • Nathan Brot
Part of the NATO Advanced Study Institutes Series book series (NSSA, volume 41)

Abstract

The steps of protein synthesis in both prokaryotes and eukaryotes involve similar reactions. One exception is the initiation process which involves more factors and appears to be more complicated in eukaryotes than in prokaryotes. The steps of elongation and termination appear to be quite similar and this chapter will summarize some aspects of peptide chain elongation and termination in eukaryotes.

Keywords

Ternary Complex Diphtheria Toxin Binary Complex Fusidic Acid Silk Gland 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Arlinghaus, R., Favelukes, G. and Schweet, R. (1963), Biochem. Biophys. Res. Commun. 11, 92–96.CrossRefGoogle Scholar
  2. 2.
    McKeehan, W.L. and Hardesty, B. (1969), J. Biol. Chem. 244, 4330–4339.PubMedGoogle Scholar
  3. 3.
    Prather, N., Ravel, J.M., Hardesty, B. and Shive, W. (1974), Biochem. Biophys. Res. Commun. 57, 578–583.PubMedCrossRefGoogle Scholar
  4. 4.
    Kemper, W.M., Merrick, W.C., Redfield, B., Liu, C.K. and Weissbach, H. (1976), Arch. Biochem. Biophys. 174, 603–612.PubMedCrossRefGoogle Scholar
  5. 5.
    Ejiri, S., Taira, H. and Shimura, K. (1973), J. Biochem. 74, 195–197.PubMedGoogle Scholar
  6. 6.
    Moon, H.M., Redfield, B., Millard, S., Vane, F. and Weissbach, H. (1973), Proc. Natl. Acad. Sci. U.S.A. 70, 3282–3286.PubMedCrossRefGoogle Scholar
  7. 7.
    Schneir, M. and Moldave, K. (1968), Biochim. Biophys. Acta 166, 58–67.PubMedCrossRefGoogle Scholar
  8. 8.
    Collins, J.F., Moon, H.M. and Maxwell, E.S. (1972), Biochemistry 11, 4187–4194.PubMedCrossRefGoogle Scholar
  9. 9.
    Liu, C.K., Legocki, A.B. and Weissbach, H. (1974), in: Lipmann Symposium: Energy Biosynthesis and Regulation in Molecular Biology, (D. Richter, ed.), pp. 384–398, Walter de Gruyter Verlag, Berlin and New York.Google Scholar
  10. 10.
    Iwasaki, K., Nagata, S., Mizumoto, K. and Kaziro, Y. (1974) J. Biol. Chem. 249, 5008–5010.PubMedGoogle Scholar
  11. 11.
    Nagata, S., Iwasaki, K. and Kaziro, Y. (1977), J. Biochem. 82, 1633–1646.PubMedGoogle Scholar
  12. 12.
    Drews, J., Bednarik, K. and Grasmuk, H. (1974), Eur. J. Biochem. 41, 217–227.PubMedCrossRefGoogle Scholar
  13. 13.
    Golinska, B. and Legocki, A.B. (1973), Biochim. Biophys. Acta 324 156–170.PubMedCrossRefGoogle Scholar
  14. 14.
    Bollini, R., Soffientini, A.N., Bertani, A. and Lanzani, G.A. I (1974) Biochemistry 13, 5431–5445.CrossRefGoogle Scholar
  15. 15.
    Slobin, L.I. and Möller, W. (1976), Eur. J. Biochem. 69, 351–366.CrossRefGoogle Scholar
  16. 16.
    Nagata, S., Motoyoshi, K. and Iwasaki, K. (1976), Biochem. Biophys. Res. Commun. 71, 933–938.CrossRefGoogle Scholar
  17. 17.
    Ejiri, S., Murakani, K. and Katsumata, T. (1977), FEBS Lett. 82, 111–114.PubMedCrossRefGoogle Scholar
  18. 18.
    Slobin, L.I. and Möller, W. (1978), Eur. J. Biochem. 84, 69–77.PubMedCrossRefGoogle Scholar
  19. 19.
    Grasmuk, H., Nolan, R.D. and Drews, J. (1978), Eur. J. Biochem. 92, 479–490.PubMedCrossRefGoogle Scholar
  20. 20.
    Slobin, L.I. and Möller, W. (1977), Biochem. Biophys. Res. Commun. 74 356–365.PubMedCrossRefGoogle Scholar
  21. 21.
    Moon, H.M., Redfield, B. and Weissbach, H. (1972), Proc. Natl. Acad. Sci. U.S.A. 69, 1249–1252.PubMedCrossRefGoogle Scholar
  22. 22.
    Nagata, S., Iwasaki, K. and Kaziro, Y. (1976), Arch. Biochem. Biophys. 172, 168–177.PubMedCrossRefGoogle Scholar
  23. 23.
    Nagata, S., Izasaki, K. and Kaziro, Y. (1976), J. Biochem. 80, 73–77.PubMedGoogle Scholar
  24. 24.
    Slobin, L.I. and Möller, W. (1975) Nature, London, 258, 252–254.CrossRefGoogle Scholar
  25. 25.
    Bolla, R. and Brot, N. (1975), Arch. Biochem. Biophys. 169, 227–236.PubMedCrossRefGoogle Scholar
  26. 26.
    Twardowski, T., Redfield, B., Kemper, W.M., Merrick, W.C. and Weissbach, H. (1976), Biochem. Biophys. Res. Commun. 71, 272–279.PubMedGoogle Scholar
  27. 27.
    Twardowski, T., Hill, J. and Weissbach, H. (1977), Arch. Biochem. Biophys. 180, 444–451.CrossRefGoogle Scholar
  28. 28.
    Iwasaki, K., Mizumoto, K., Tanaka, M. and Kaziro, Y. (1973), J. Biochem. 74, 849–852.PubMedGoogle Scholar
  29. 29.
    Motoyoshi, K., Iwasaki, K. and Kaziro, Y. (1977), J. Biochem. 82, 145–155.PubMedGoogle Scholar
  30. 30.
    Motoyoshi, K. and Iwasaki, K. (1977), J. Biochem. 82, 703–708.PubMedGoogle Scholar
  31. 31.
    Hachmann, J., Miller, D.L. and Weissbach, H. (1971), Arch. Biochem. Biophys. 147, 457–466.PubMedCrossRefGoogle Scholar
  32. 32.
    Moon, H.M. and Weissbach, H. (1972), Biochem. Biophys. Res. Commun. 46, 254–262.PubMedCrossRefGoogle Scholar
  33. 33.
    Legocki, A.B., Redfield, B. and Weissbach, H. (197H), Arch. Biochem. Biophys. 161, 709–712.Google Scholar
  34. 34.
    Miller, D.L. and Weissbach, H. (1970), Arch. Biochem. Biophys. 141, 26–37.PubMedCrossRefGoogle Scholar
  35. 35.
    Slobin, L.I. and Moller, W. (1976), Eur. J. Biochem. 69, 367–375.CrossRefGoogle Scholar
  36. 36.
    Nolan, R.K., Grasmuk, H., Hogenauer, G. and Drews, J. (1974), Eur. J. Biochem. 49 601–609.CrossRefGoogle Scholar
  37. 37.
    Weissbach, H., Redfield, B. and Moon, H.M. (1973), Arch. Biochem. Biophys. 156, 267–275.PubMedCrossRefGoogle Scholar
  38. 38.
    Lin, S.Y., Mc Keehan, W.L., Culp, W. and Hardesty, B. (1969), J. Biol. Chem. 244, 4340–4350.PubMedGoogle Scholar
  39. 39.
    Nolan, R.D., Grasmuk, H. and Drews, J. (1975), Eur. J. Biochem. 50, 391–402.PubMedCrossRefGoogle Scholar
  40. 40.
    Harris, R.J. and Pestka, S. (1977), in: Molecular Mechanisms of Protein Biosynthesis (H. Weissbach and S. Pestka, eds.) pp. 413–465, Academic Press, New York.Google Scholar
  41. 41.
    Pestka, S. (1977), in: Molecular Mechanisms of Protein Biosynthesis (H. Weissbach and S. Pestka eds.) pp. 467–553, Academic Press, New York.Google Scholar
  42. 42.
    Raeburn, S., Collins, J.F., Moon, H.M. and Maxwell, E.S. (1971), J. Biol. Chem. 246, 1041–1048.PubMedGoogle Scholar
  43. 43.
    Galasinski, W. and Moldave, K. (1969), J. Biol. Chem. 244, 6527–6532.PubMedGoogle Scholar
  44. 44.
    Mizumoto, K., Iwasaki, K., Tanaka, M. and Kaziro, Y. (197H), J. Biochem. 75, 1047–1056.Google Scholar
  45. 45.
    Taira, H., Ejiri, S. and Shimura, K. (1972), J. Biochem. 72, 1527–1535.PubMedGoogle Scholar
  46. 46.
    Henriksen, O., Robinson, E.A. and Maxwell, E.S. (1975), J. Biol. Chem. 250, 720–72H.PubMedGoogle Scholar
  47. 47.
    Muzumoto, K., Iwasaki, K., Kaziro, Y., Nojiri, C. and Yamada, Y. (197H), J. Biochem. 75, 1057–1062.Google Scholar
  48. 48.
    Twardowski, T. and Legocki, A.B. (1973), Biochim. Biophys. Acta 324, 171–183.PubMedCrossRefGoogle Scholar
  49. 49.
    Robinson, E.A. and Maxwell, E.S. (1972), J. Biol. Chem. 247, 7023–7028.PubMedGoogle Scholar
  50. 50.
    Honjo, T., Nishizuka, Y., Hayaishi, O. and Kato, I. (1968), J. Biol. Chem. 243, 3553–3555.PubMedGoogle Scholar
  51. 51.
    Schneider, J.A., Raeburn, S. and Maxwell, E.S. (1968), Biochem. Biophys. Res. Commun. 33, 177–181.PubMedCrossRefGoogle Scholar
  52. 52.
    Skogerson, L. and Moldave, K. (1968), J. Biol. Chem. 243, 5354–5360.PubMedGoogle Scholar
  53. 53.
    Skogerson, L. and Moldave, K. (1968), J. Biol. Chem. 243, 5361–5367.PubMedGoogle Scholar
  54. 54.
    Skogerson, L. and Moldave, K, (1967), Biochem. Biophys. Res. Commun. 27, 568–572.PubMedCrossRefGoogle Scholar
  55. 55.
    Smulson, M.E. and Rideau, C. (1970), J. Biol. Chem. 245, 5350–5353.PubMedGoogle Scholar
  56. 56.
    Arai, N., Arai, K. and Kaziro, Y. (1977), J. Biochem. 82, 687–694.PubMedGoogle Scholar
  57. 57.
    Baligo, B.S. and Munro, H.N. (1972), Biochim. Biophys. Acta 277, 368–383.CrossRefGoogle Scholar
  58. 58.
    Mizumoto, K., Iwasaki, K. and Kaziro, Y. (1974), J. Biochem. 76, 1269–1280.PubMedGoogle Scholar
  59. 59.
    Chaung, D.M. and Weissbach, H. (1972), Arch. Biochem. Biophys. 152, 114–124.CrossRefGoogle Scholar
  60. 60.
    Bodley, J.W. and Lin, L. (1970),* Nature, London, 227, 60–62.Google Scholar
  61. 61.
    Bermek, E. and Matthaei, H. (1971), Biochemistry 10, 4906–4912.PubMedCrossRefGoogle Scholar
  62. 62.
    Montanaro, L., Sperti, S. and Mattioli, A. (1971), Biochim. Biophys. Acta 238, 493–497.PubMedCrossRefGoogle Scholar
  63. 63.
    Mizumoto, K., Iwasaki, K. and Kaziro, Y. (1974), J. Biochem. 76, 1269–1280.PubMedGoogle Scholar
  64. 6k.
    Henriksen, O., Robinson, E.A. and Maxwell, E.S. (1975), J. Biol. Chem. 250, 725–730.PubMedGoogle Scholar
  65. 65.
    Inoue-Yokosawa, N., Ishikawa, C. and Kaziro, Y. (197*0, J. Biol. Chem. 249, 4321–4323.Google Scholar
  66. 66.
    Belitsina, N.V., Glukhove, M.A. and Spirin, A.S. (1975), FEBS Lett. 54, 35–38.PubMedCrossRefGoogle Scholar
  67. 67.
    Modolell, J., Girbes, T. and Bazquez, D. (1975), FEBS Lett. 60, 109–113.PubMedCrossRefGoogle Scholar
  68. 68.
    Belitsina, N.V., Glukhova, M.A. and Spirin, A.S. (1976), J. Mol. Biol. 108, 609–613.PubMedCrossRefGoogle Scholar
  69. 69.
    Girbes, T., Vasquez, D. and Modolell, J. (1976), Eur. J. Biochim. 67, 257–265.CrossRefGoogle Scholar
  70. 70.
    Tanaka, M., Iwasaki, K. and Kaziro, Y. (1977), J. Biochem. 82, 1035–1043.PubMedGoogle Scholar
  71. 71.
    Baliga, B.S., Schechtman, M.G. and Munro, H.N. (1973), Biochem. Biophys. Res. Commun. 51, 406–413.PubMedCrossRefGoogle Scholar
  72. 72.
    Nombela, C. and Ochoa, S. (1973), Proc. Natl. Acad. Sci. U.S.A. 70, 3556–3560.PubMedCrossRefGoogle Scholar
  73. 73.
    Mc Keehan, W. (1972), Biochem. Biophys. Res. Commun. 48, 1117–1122.PubMedCrossRefGoogle Scholar
  74. 74.
    Collier, R.J. (1975), Bacteriol. Rev. 39, 5–85.Google Scholar
  75. 75.
    Pappenheimer, A.M., Jr. (1977), Ann. Rev. Biochem. 46, 69–94.PubMedCrossRefGoogle Scholar
  76. 76.
    Strauss, N. and Hendee, D.D. (19597, J. Exp. Med. 109, 145–163.Google Scholar
  77. 77.
    Collier, R.J. and Pappenheimer, A.M., Jr. (1964), J. Exp. Med. 120, 1019–1039.PubMedCrossRefGoogle Scholar
  78. 78.
    Collier, R.J. (1967), J. Mol. Biol. 25, 83–98.PubMedCrossRefGoogle Scholar
  79. 79.
    Goor, R.S. and Pappenheimer, A.M., Jr. (1967), J. Exp. Med. 126, 899–912.PubMedCrossRefGoogle Scholar
  80. 80.
    Goor, R.S. and Pappenheimer, A.M., Jr. (1967), J. Exp. Med. 126, 913–921.PubMedCrossRefGoogle Scholar
  81. 81.
    Raeburn, S., Goor, R.S., Schneider, J.A. and Maxwell, E.S. (1968) Proc. Natl. Acad. Sci. U.S.A. 61, 1428–1434.PubMedCrossRefGoogle Scholar
  82. 82.
    Van Ness, B.G., Howard, J.B. and Bodley, J.W. (1978), J. Biol. Chem. 253, 8687–8690.PubMedGoogle Scholar
  83. 83.
    Robinson, E.A., Henriksen, D. and Maxwell, E.S. (1974), J. Biol. Chem. 249, 5088–5093.PubMedGoogle Scholar
  84. 84.
    Brown, B.A. and Bodley, J.W. (1979), FEBS Lett. 103, 253–255.PubMedCrossRefGoogle Scholar
  85. 85.
    Van Ness, B.G., Howard, J.B. and Bodley, J.W. (1980), J. Biol. Chem., in press.Google Scholar
  86. 86.
    Moehring, J.M., Moehring, J.J. and Danley, D.E. (1980), Proc. Natl. Acad. Sci. U.S.A. 77, 1010–1014.PubMedCrossRefGoogle Scholar
  87. 87.
    Van Ness, B.G. and Bodley, J.W. (1980), FEBS Lett., in press.Google Scholar
  88. 88.
    Goldstein, J.L., Beaudet, A.L. and Caskey, C.T. (1970), Proc. Natl. Acad; Sci. U.S.A. 67, 99–105.PubMedCrossRefGoogle Scholar
  89. 89.
    Beaudet, A.L. and Caskey, C.T. (1971) Proc. Natl. Acad. Sci. U.S.A. 68, 619–624.PubMedCrossRefGoogle Scholar
  90. 90.
    Ilan, J. (1973), J. Mol. Biol. 77., 437–448.PubMedCrossRefGoogle Scholar
  91. 91.
    Innanen, V.T. and Nicholls, D.M. (1973), Biochim. Biophys. Acta 324, 533–544.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Nathan Brot
    • 1
  1. 1.Roche Institute of Molecular BiologyNutleyUSA

Personalised recommendations