Ability of Liver Homogenates and Proteins to Reduce the Mutagenic Effect of Diesel Exhaust Particulates

  • Yi Y. Wang
  • Eddie T. Wei
Part of the Environmental Science Research book series (ESRH, volume 22)


An estimate by the U.S. Environmental Protection Agency (EPA) indicates that by 1985, 25% of the automobiles produced in the United States may be diesel powered, because diesel engines provide greater fuel economy than do spark-ignition gasoline engines (Santodonato et al., 1978). Automotive diesel engines may emit from 30 to 80 times more particulates than a comparable gasoline engine (Springer and Baines, 1977). Concern has been expressed about the potential health hazards of these particulates, since extracts of diesel particulates contain chemicals that are mutagenic in the Ames Salmonella typhimurium bioassay (Huisingh et al., 1978; Wei et al., 1980), a short-term test for determining the mutagenic and carcinogenic potential of chemicals (Ames and McCann, 1976).


Diesel Engine Mutagenic Activity Liver Homogenate Diesel Exhaust Diesel Exhaust Particulate 
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Copyright information

© Springer Science+Business Media New York 1980

Authors and Affiliations

  • Yi Y. Wang
    • 1
  • Eddie T. Wei
    • 1
  1. 1.School of Public HealthUniversity of CaliforniaBerkeleyUSA

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