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Mutagenicity of Nitrogen Compounds from Synthetic Crude Oils: Collection, Separation, and Biological Testing

  • T. K. Rao
  • J. L. Epler
  • M. R. Guerin
  • B. R. Clark
  • C.-h. Ho
Part of the Environmental Science Research book series (ESRH, volume 22)

Abstract

Short-term mutagenesis assays have been used to test complex environmental mixtures, in order to 1) serve as predictors of long-range health effects, 2) guide chemical separation procedures for the isolation and concentration of biologically active materials, 3) identify chemical agents responsible for biological activity, and 4) determine priorities for further, extensive testing. Organic extraction coupled with chemical-class fractionation is a prerequisite for most of these assays.

Keywords

Polycyclic Aromatic Hydrocarbon Mutagenic Activity Basic Fraction Neutral Fraction Mutagenicity Assay 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer Science+Business Media New York 1980

Authors and Affiliations

  • T. K. Rao
    • 1
  • J. L. Epler
    • 1
  • M. R. Guerin
    • 1
  • B. R. Clark
    • 1
  • C.-h. Ho
    • 1
  1. 1.Biology and Analytical Chemistry DivisionsOak Ridge National LaboratoryOak RidgeUSA

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