Mutagenicity of Nitrogen Compounds from Synthetic Crude Oils: Collection, Separation, and Biological Testing
Short-term mutagenesis assays have been used to test complex environmental mixtures, in order to 1) serve as predictors of long-range health effects, 2) guide chemical separation procedures for the isolation and concentration of biologically active materials, 3) identify chemical agents responsible for biological activity, and 4) determine priorities for further, extensive testing. Organic extraction coupled with chemical-class fractionation is a prerequisite for most of these assays.
KeywordsPolycyclic Aromatic Hydrocarbon Mutagenic Activity Basic Fraction Neutral Fraction Mutagenicity Assay
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