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The Effects of Endotoxin on Macrophages and T-Lymphocytes

  • David L. Rosenstreich
  • Stefanie N. Vogel

Abstract

The immune response is generated by a complex series of interactions between three major lymphoreticular cell types, macrophages and B and T lymphocytes (Fig. 1). This response is initiated by the interaction of an external stimulus, such as an antigen or mitogen, with each of all of these cells. The initial stimulation also results in the production of a number of soluble intercellular messengers i.e., lymphokines or monokines, that act within the system to produce a marked amplification of the response.

Keywords

Migration Inhibitory Factor Kill Tumor Cell Bacterial Lipopolysaccharide Macrophage Secretion Lymphocyte Activate Factor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • David L. Rosenstreich
    • 1
    • 2
    • 3
  • Stefanie N. Vogel
    • 1
    • 2
    • 3
  1. 1.Department of MedicineAlbert Einstein College of MedicineBronxUSA
  2. 2.Department of MicrobiologyAlbert Einstein College of MedicineBronxUSA
  3. 3.Laboratory of Microbiology and ImmunologyNational Institute of Dental Research National Institutes of HealthBethesdaUSA

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