Bifurcations in Insect Morphogenesis I

  • Stuart A. Kauffman
Part of the NATO Advanced Study Institutes Series book series (NSSB, volume 75)


The past decade has witnessed a renewal of deep interest in the problem of pattern formation in developmental biology. In large measure, the resurgence of enthusiasm coincides with Wolpert’s reformulation of this fundamental problem in terms of the concept of positional information [Wolpert, 1969, 1971]. Novel features of Wolpert’s theory have led both to proposals of alternative “coordinate systems” supplying positional information, and to a rich variety of experiments designed to test the alternatives. The present article provides a brief review of the major alternatives which leads to the formulation of a new class of models based on the unrecognized, but common capacity of biochemical reaction-diffusion systems to generate transverse (cross) gradients in growing asymmetrical tissue domains.


Positional Information Imaginal Disc Polar Model Wing Disc Complementary Fragment 


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Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • Stuart A. Kauffman
    • 1
  1. 1.Department of Biochemistry and BiophysicsUniversity of Pennsylvania School of MedicinePhiladelphiaUSA

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