Abstract
One of the most important and interesting membrane-based processes is the transport of ions in and out of cells and cell organelles. In the study of ion transport across membranes, the concept of ionophoric activity has emerged. The term ionophoric activity has been used to mean various properties of a substance, depending on the method used to assay for the ionophorous material. Using the characteristic common to all methods, we may generally define an ionophore as a substance that enhances the movement or incorporation of an ion from an aqueous phase into a hydrophobic phase (Shamoo and Goldstein, 1977). An ionophore so defined is not necessarily involved in ion transport across biological membranes.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Abramson, J. J., and Shamoo, A. E. (1978). J. Membr. Biol. 44, 233–257.
Allen, G. (1977). Proceedings FEBS 11th Meeting, Copenhagen, Symposium A4, Vol. 45, pp. 159–168.
Berman, M. D., McIntosh, D. B., and Kench, J. E. (1977). J. Biol. Chem. 252, 994–1001.
Hasselbach, W. (1978). Biochim. Biophys. Acta 515, 23–53.
Hidalgo, C. (1980). Biochem. Biophys. Res. Commun. 92, 757–765.
Klip, A., and MacLennan, D. H. (1978). In Frontiers of Biological Energetics: Electrons to Tissues (A. Scarpa, F. Dutton, and J. Leigh, eds.), Academic Press, New York.
Klip, A., Reithmeier, R. A. F., and MacLennan, D. H. (1980). J. Biol. Chem. 255, 6562–6568.
MacLennan, D. H., Reithmeier, R. A. F., Shoshan, V., Campbell, K. P., LeBel, D., Herrmann, T. R., and Shamoo, A. E. (1980). Ann. N.Y. Acad. Sci., 358, 138–148.
Masuda, H., and de Meis, L. (1974). Biochim. Biophys. Acta 332, 313–315.
Ratkje, S. K., and Shamoo, A. E. (1980). Biophys. J. 30, 523–530.
Scott, T. L. (1979). Ph.D. thesis, University of Rochester.
Scott, T. L. (1979). Ph.D. thesis, University of Rochester.
Shamoo, A. E. (1979). In Physical Chemical Aspects of Cell Surface Events in Cellular Regulation (C. DeLisi and R. Blumenthal, eds.), pp. 59–68, Elsevier/North-Holland, Amsterdam.
Shamoo, A. E., and Goldstein, D. A. (1977). Biochim. Biophys. Acta 472, 13–53.
Shamoo, A. E., and MacLennan, D. H. (1974). Proc. Natl. Acad. Sci. USA 71, 3522–3526.
Shamoo, A. E., and MacLennan, D. H. (1975). J. Membr. Biol. 25, 65–74.
Shamoo, A. E., and Ryan, T. E. (1975). Ann. N.Y. Acad. Sci 264, 83–97.
Shamoo, A. E., Ryan, T. E., Stewart, P. E., and MacLennan, D. H. (1976). J. Biol. Chem. 251, 4147–4154.
Stewart, P. S., and MacLennan, D. H. (1974). J. Biol. Chem. 249, 985–993.
Stewart, P. S., MacLennan, D. H., and Shamoo, A. E. (1976). J. Biol. Chem. 251, 712–719.
Thorley-Lawson, D. A., and Green, N. M. (1975). Eur. J. Biochem. 59, 193–200.
Thorley-Lawson, D. A., and Green, N. M. (1977). Biochem. J. 167, 739–748.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1982 Plenum Press, New York
About this chapter
Cite this chapter
Herrmann, T.R., Shamoo, A.E. (1982). Isolation and Use of lonophores for Studying Ion Transport across Natural Membranes. In: Martonosi, A.N. (eds) Membranes and Transport. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4082-9_75
Download citation
DOI: https://doi.org/10.1007/978-1-4684-4082-9_75
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-4084-3
Online ISBN: 978-1-4684-4082-9
eBook Packages: Springer Book Archive