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Isolation and Use of lonophores for Studying Ion Transport across Natural Membranes

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Abstract

One of the most important and interesting membrane-based processes is the transport of ions in and out of cells and cell organelles. In the study of ion transport across membranes, the concept of ionophoric activity has emerged. The term ionophoric activity has been used to mean various properties of a substance, depending on the method used to assay for the ionophorous material. Using the characteristic common to all methods, we may generally define an ionophore as a substance that enhances the movement or incorporation of an ion from an aqueous phase into a hydrophobic phase (Shamoo and Goldstein, 1977). An ionophore so defined is not necessarily involved in ion transport across biological membranes.

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© 1982 Plenum Press, New York

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Herrmann, T.R., Shamoo, A.E. (1982). Isolation and Use of lonophores for Studying Ion Transport across Natural Membranes. In: Martonosi, A.N. (eds) Membranes and Transport. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4082-9_75

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  • DOI: https://doi.org/10.1007/978-1-4684-4082-9_75

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4084-3

  • Online ISBN: 978-1-4684-4082-9

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