Abstract
Cytochrome reductase (ubiquinol: cytochrome c reductase, EC 1.10.2.2) is a major enzyme of the mitochondrial oxidative phosphorylation system (Rieske, 1976; Crane, 1977; Hatefi and Galante, 1978; von Jagow and Sebald, 1980). The enzyme catalyzes electron transfer from ubiquinone to cytochrome c and utilizes the energy of the redox reaction to translocate protons across the mitochondrial inner membrane (Mitchell, 1975; Papa, 1976). The transmembranous proton gradient can be used by the ATP synthetase to drive the synthesis of ATP from ADP and phosphate (Boyer et al., 1977).
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References
Barrell, B. G., Anderson, S., Bankier, A. T., de Bruijn, M. H. L., Chen, E., Coulson, A. R., Drouin, J., Epheron, J. C., Nierlich, D. P., Roe, B., Sanger, F., Schreier, P. H., Smith, A. J. H., Staden, R., and Young, J. G. (1980). In Biological Chemistry of Organelle Formation (T. Bücher, W. Sebald, and H. Weiss, eds.), pp. 11–26, Springer-Verlag, Berlin.
Bosshard, H. R., Zurrer, M., Schägger, H., and von Jagow, G. (1979). Biochem. Biophys. Res. Commun. 89, 250–258.
Boyer, P. D., Chance, B., Ernster, L., Mitchell, P., Racker, E., and Slater, E. C. (1977). Annu. Rev. Biochem. 46, 955–1026.
Crane, F. L. (1977). Annu. Rev. Biochem. 46, 439–469.
Engel, W. D., Schägger, H., and von Jagow, G. (1980). Biochim. Biophys. Acta 592, 211–222.
Hatefi, Y., and Galante, Y. M. (1978). In Energy Conservation in Biological Membranes (G. Schäfer and M. Klingenberg, eds.), pp. 19–30, Springer-Verlag, Berlin.
Holloway, P. S. (1973). Anal. Biochem. 53, 304–308.
Hovmöller, S., Leonard, K., and Weiss, H. (1981). FEBS Lett. 123, 118–122.
Katan, M. B., Pool, L., and Groot, G. S. P. (1976). Eur. J. Biochem. 65, 95–105.
König, B. W., Schilder, L. T. M., Tervoort, M. J., and Van Gelder, B. F. (1980). Biochim. Biophys. Acta, 621, 283–295.
Leonard, K., Wingfield, P., Arad, T., and Weiss, H. (1981). J. Mol. Biol. 149, 259–274.
Li, Y., Leonard, K., and Weiss, H. (1981). Eur. J. Biochem. 116, 199–205.
Mitchell, P. (1975). FEBS Lett. 56, 1–6.
Papa, S. (1976). Biochim. Biophys. Acta 456, 39–84.
Rieske, J. S. (1976). Biochim. Biophys. Acta 456, 195–247.
Trumpower, B. L., and Edwards, C. A. (1979). J. Biol. Chem. 254, 8697–8706.
Tzagoloff, A., and Nobrega, G. F. (1980). In Biological Chemistry of Organelle Formation (T. Bücher, W. Sebald, and H. Weiss, eds.), pp. 1–10, Springer-Verlag, Berlin.
Tzagoloff, A., Akai, A., Needleman, R. B., and Zulch, G. (1975). J. Biol. Chem. 250, 8236–8242.
von Jagow, G., and Sebald, W. (1980). Annu. Rev. Biochem. 49, 281–314.
Wakabayashi, S., Matsubara, H., Kim, C. H., Kawai, K., and King, T. E. (1980). Biochem. Biophys. Res. Commun. 97, 1548–1554.
Weiss, H., and Kolb, H. J. (1979). Eur. J. Biochem. 99, 139–149.
Weiss, H., and Wingfield, P. (1979). Eur. J. Biochem. 99, 139–149.
Weiss, H., and Ziganke, B. (1974). Eur. J. Biochem. 41, 63–71.
Wingfield, P., Arad, T., Leonard, K., and Weiss, H. (1979). Nature (London) 280, 696–697.
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Leonard, K., Weiss, H. (1982). The Structure of Mitochondrial Ubiquinol: Cytochrome c Reductase. In: Martonosi, A.N. (eds) Membranes and Transport. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4082-9_65
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DOI: https://doi.org/10.1007/978-1-4684-4082-9_65
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