Transport of Ions and the Membrane Potential of Mitochondria

  • Henry Tedeschi


In contemporary thought, the electrochemical gradient of H+ in mitochondria, the so-called protonmotive force (\({{\mu }_{{{\text{H}}^{+}}}}\)), is considered directly responsible for the transport of ions and the phosphorylation of ADP.


Membrane Potential Mitochondrial Membrane Electrochemical Gradient Nernst Equation Lipophilic Cation 
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  1. Åkerman, K. E. O. (1978). FEBS Lett. 93, 293–296.CrossRefGoogle Scholar
  2. Anagnosti, E., and Tedeschi, H. (1970). J. Cell Biol. 47, 520–525.CrossRefGoogle Scholar
  3. Azzi, A., and Azzone, G. F. (1967). Biochim. Biophys. Acta 135, 444–453.CrossRefGoogle Scholar
  4. Azzone, G. F., Bragadin, M., Pozzan, T., and Dell’Antone, P. (1976). Biochim. Biophys. Acta 459, 96–109.Google Scholar
  5. Azzone, G. F., Borlotto, F., and Zanotti, A. (1978a). FEBS Lett. 96, 135–140.CrossRefGoogle Scholar
  6. Azzone, G. F., Pozzan, T., Viola, E., and Arslan, P. (19786). Biochim. Biophys. Acta 501, 317–329.Google Scholar
  7. Azzone, G. F., Zanotti, A., and Colonna, R. (1978c). FEBS Lett. 96, 141–147.CrossRefGoogle Scholar
  8. Bowman, C., and Tedeschi, H. (1980). Science 209, 1251–1252.CrossRefGoogle Scholar
  9. Brierley, G. P., Bachman, E., and Green, D. E. (1962). Proc. Natl. Acad. Sci. USA 48, 1928–1935.CrossRefGoogle Scholar
  10. Brierley, G. P., Jurkowitz, M., Chavez, E., and Jung, D. W. (1977). J. Biol. Chem. 252, 7932–7939.Google Scholar
  11. Carafoli, E. (1979). FEBS Lett. 104, 1–5.CrossRefGoogle Scholar
  12. Chavez, E., Jung, D. W., and Brierley, G. P. (1977). Arch. Biochem. Biophys. 183 460–470.CrossRefGoogle Scholar
  13. Cohen, S. M., Ogawa, S., Rottenberg, H., Glynn, P., Yamane, T., Brown, T. R., and Shulman, R. G. (1978). Nature (London) 273, 554–556.CrossRefGoogle Scholar
  14. Colonna, R., Massari, A., and Azzone, G. F. (1973). Eur. J. Biochem. 34, 577–585.CrossRefGoogle Scholar
  15. Crompton, M., Hediger, M., and Carafoli, E. (1978). Biochem. Biophys. Res. Commun. 80, 540–546.CrossRefGoogle Scholar
  16. Deutsch, C., Erecinska, M., Werrlein, R., and Silver, I. A. (1979). Proc. Natl. Acad. Sci. USA 76, 2175–2179.CrossRefGoogle Scholar
  17. Diwan, J. J., and Lehrer, P. H. (1977). Biochem. Soc. Trans. 5, 203–204.Google Scholar
  18. Diwan, J. J., and Lehrer, P. H. (1978). Membr. Biochem. 1, 43–60.CrossRefGoogle Scholar
  19. Diwan, J. J., and Tedeschi, H. (1975). FEBS Lett. 60, 176–179.CrossRefGoogle Scholar
  20. Diwan, J. J., Markoff, M., and Lehrer, P. H. (1977). Indian J. Biochem. Biophys. 14, 342–346.Google Scholar
  21. Diwan, J. J., Dazé, M., Richardson, R., and Aronson, D. (1979). Biochemistry 18, 2590–2595.CrossRefGoogle Scholar
  22. Diwan, J. J., Aronson, D., and Gonsalves, N.O. (1980). J. Bioenerg. Biomembr. 12, 205–212.CrossRefGoogle Scholar
  23. Fiskum, G., and Lehninger, A. L. (1980). Fed. Proc. 39, 2432–2436.Google Scholar
  24. Fiskum, G., G., Reynafarje, B., and Lehninger, A. L. (1979). J. Biol. Chem. 254, 6288–6295.Google Scholar
  25. Gauthier, L. M., and Diwan, J. J. (1979). Biochem. Biophys. Res. Commun. 87, 1072–1079.CrossRefGoogle Scholar
  26. Harris, E. J. (1978). Biochem. J. 176, 983–991.Google Scholar
  27. Harris, E. J., Catlin, G., and Pressman, B. C. (1967). Biochemistry 6, 1360–1369.CrossRefGoogle Scholar
  28. Higuti, T., Arakaki, N., Niimi, S., Nakasima, S., Saito, R., Tani, I., and Ota, F. (1980). J. Biol. Chem. 255, 7631–7636.Google Scholar
  29. Izzard, S., and Tedeschi, H. (1970). Proc. Natl. Acad. Sci. USA 67, 702–709.CrossRefGoogle Scholar
  30. Johnson, J. H., and Pressman, B. C. (1969). Arch. Biochem. Biophys. 132, 139–145.CrossRefGoogle Scholar
  31. Judah, D. W., Ahmed, K., McLean, A. E. M., and Christie, G. M. (1965). Biochim. Biophys. Acta 94, 452–460.CrossRefGoogle Scholar
  32. Jung, D. W., Chavez, E., and Brierley, G. P. (1977). Arch. Biochem. Biophys. 183, 452–459.CrossRefGoogle Scholar
  33. Kamo, N., Muratsugu, M., Kurihara, K., and Kobatake, Y. (1976). FEBS Lett. 72, 247–250.CrossRefGoogle Scholar
  34. Klingenberg, M., and Rottenberg, H. (1977). Eur. J. Biochem. 73, 125–130.CrossRefGoogle Scholar
  35. Lehninger, A. L. (1974). Proc. Natl. Acad. Sci. USA 71, 1520–1524.CrossRefGoogle Scholar
  36. Ligeti, E., and Fonyd, A. (1977). FEBS Lett. 79, 33–36.CrossRefGoogle Scholar
  37. Massari, S., and Azzone, G. F. (1970). Eur. J. Biochem. 12, 310–318.CrossRefGoogle Scholar
  38. Massari, S., Frigeri, L., and Azzone, G. F. (1972). J. Membr. Biol. 9, 71–82.CrossRefGoogle Scholar
  39. Mitchell, P., and Moyle, J. (1969). Eur. J. Biochem. 7, 471–484.CrossRefGoogle Scholar
  40. Ogawa, S., Shen, C., and Castillo, C. L. (1980). Biochim. Biophys. Acta 590, 159–169.CrossRefGoogle Scholar
  41. Padan, E., and Rottenberg, H. (1973). Eur. J. Biochem. 40, 431–437.CrossRefGoogle Scholar
  42. Parr, D. R., and Harris, E. J. (1976). Biochem. J. 158, 289–294.Google Scholar
  43. Pozzan, T., and Azzone, G. F. (1976). FEBS Lett., 71, 62–66.CrossRefGoogle Scholar
  44. Pressman, B. C. (1968). Fed. Proc. 27, 1283–1288.Google Scholar
  45. Quintinilha, A. T., and Packer, L. (1977). FEBS Lett. 78, 161–165.CrossRefGoogle Scholar
  46. Rossi, C., Azzi, A., and Azzone, G. F. (1967). J. Biol. Chem. 242, 951–957.Google Scholar
  47. Rottenberg, H. (1973). J. Membr. Biol. 11, 117–137.CrossRefGoogle Scholar
  48. Rottenberg, H., and Solomon, A. K. (1969). Biochim. Biophys. Acta 93, 48–57.Google Scholar
  49. Scarpa, A., and Azzone, G. F. (1970). Eur. J. Biochem. 12, 328–335.CrossRefGoogle Scholar
  50. Shen, C., Boens, C. C., and Ogawa, S. (1980). Biochem. Biophys. Res. Commun. 93, 243–249.Google Scholar
  51. Tedeschi, H. (1980). Biol. Rev. 55, 171–206.CrossRefGoogle Scholar
  52. Walsh Kinnally, K., and Tedeschi, H. (1976). FEBS Lett. 62, 41–46.CrossRefGoogle Scholar
  53. Walsh Kinnally, K., Maloff, B. L., and Tedeschi, H. (1978). Biochemistry 17, 3419–3428.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Henry Tedeschi
    • 1
  1. 1.Department of Biological SciencesState University of New YorkAlbanyUSA

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