Genetic Approaches for Studying Protein Localization
The process of protein compartmentalization is common to both prokaryotic and eukaryotic cells. In eukaryotic cells, proteins are apportioned specifically to the cytoplasm, to any of a variety of organelles, or to the surrounding medium. While less complex, gram-negative bacteria also specifically localize proteins to subcellular compartments: cytoplasm, inner membrane, outer membrane, or periplasm (the space between the inner and the outer membrane).
KeywordsCoat Protein Protein Localization Maltose Binding Protein Hybrid Protein Secretory Apparatus
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- Bassford, P. J., Jr., Silhavy, T. J., and Beckwith, J. R. (1979). J. Bacteriol. 139, 19–31.Google Scholar
- Sancar, A., Hack, A. M., and Rupp, W. D. (1979). J. Bacteriol. 137, 692–693.Google Scholar
- Silhavy, T. J., Shuman, H. A., Beckwith, J., and Schwartz, M. (1977). Proc. Natl. Acad. Sci. USA 74, 5411–5415Google Scholar
- Silhavy, T. J., Bassford, P. J., Jr., and Beckwith, J. R. (1979). In Bacterial Outer Membranes: Biogenesis and Functions (M. Inouye, ed.), pp. 203–254, Wiley, New York.Google Scholar
- Wanner, B. L., Sarthy, A., and Beckwith, J. (1979). J. Bacteriol. 140, 229–239.Google Scholar