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Multifunctional Glucose-6-phosphatase of Endoplasmic Reticulum and Nuclear Membrane

  • Robert C. Nordlie

Abstract

Work beginning in 1963 in our laboratory (Nordlie and Arion, 1964) and that of Stetten (Stetten and Taft, 1964) has shown glucose-6-phosphatase to be a multifunctional enzyme capable of synthesis of glucose-6-P via potent phosphotransferase activities [reaction (1)] as well as glucose-6-P hydrolysis [reaction (2)]. Since that time a major emphasis has been placed upon PP i and carbamyl-P as phosphoryl donors (RP) and glucose as acceptor, although other compounds also will function as substrates.

Keywords

Nuclear Membrane Microsomal Preparation Pyridoxal Phosphate Disulfonic Acid Major Emphasis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Robert C. Nordlie
    • 1
  1. 1.Department of BiochemistryUniversity of North Dakota School of MedicineGrand ForksUSA

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