Heterogeneity of Human Melanoma-Associated Antigens Revealed by Alloantisera and Xenoantisera

  • Peter B. Dent
  • Shuen-Kuei Liao


As repeatedly stressed by other authors in this volume, human malignant melanoma is a good model for the study of tumor immunology. A number of fundamental questions have been raised in this model, and reliable answers may now be emerging. These questions include the following: (1) Do human tumor-specific antigens that function as rejection antigens exist? (2) Are these antigens immunogenic in man, and if they are, how should they be measured? (3) Are there antigens on melanoma cells that are recognized only by heterologous species, and if there are, might they be of any use in immunodiagnosis and therapy?


Melanoma Cell Human Leukocyte Antigen Melanoma Patient Melanoma Cell Line Human Melanoma 
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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Peter B. Dent
    • 1
    • 2
  • Shuen-Kuei Liao
    • 1
    • 2
  1. 1.Departments of Pediatrics and PathologyMcMaster UniversityHamiltonCanada
  2. 2.The Ontario Cancer Treatment & Research Foundation (Hamilton Clinic)HamiltonCanada

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