Shedding and Degradation of Cell-Surface Macromolecules and Melanoma-Associated Antigens by Human Melanoma

  • Jean-Claude Bystryn


Tumor antigens, particularly those expressed on the surface of cells, are believed to have a critical though complex effect on tumor growth. They may stimulate immune responses and thus increase resistance to cancer. Conversely, alone or in complex with antibodies, they may interfere with humoral and cellular immune destruction of malignant cells and thus may enhance tumor growth. Since these effects can be mediated by soluble tumor antigens, the factors that influence their accumulation in body fluids may have an important impact on tumor growth.


Melanoma Cell Human Melanoma Murine Melanoma Cell Unlabeled Cell Melanoma Associate Antigen 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Jean-Claude Bystryn
    • 1
  1. 1.Department of DermatologyNew York University School of MedicineNew YorkUSA

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