Antigens in Human Melanomas Detected by Using Monoclonal Antibodies as Probes

  • Karl Erik Hellström
  • Ingegerd Hellström


Some of the first evidence that human patients can react immunologically to their own tumors was obtained during the late 1960s when both humoral and cellular immune responses to putative tumor antigens were first reported (for reviews, see Herberman, 1974; K. E. Hellström and Brown, 1979). However, the nature of the antigens that were the targets in the reactions observed, and their degree of tumor specificity (if any), have been the subjects of much controversy.


Monoclonal Antibody Melanoma Cell Binding Assay Tumor Antigen Human Melanoma 
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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Karl Erik Hellström
    • 1
    • 2
  • Ingegerd Hellström
    • 1
    • 2
  1. 1.Division of Tumor ImmunologyFred Hutchinson Cancer Research CenterSeattleUSA
  2. 2.Departments of Pathology (K. E. H.) and Microbiology/ Immunology (I. H.)University of WashingtonSeattleUSA

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