Dynamic Laser Scattering Study of Sperm Migration Through Cervical Mucus

  • Wylie I. Lee
Part of the NATO Advanced Study Institutes Series book series (NSSB, volume 73)


Migration of spermatozoa through the cervix is of great interest in human reproductive biology, and is important in fertility studies. The penetration of spermatozoa into cervical mucus depends on sperm motility and also on the molecular structure of cervical mucus. We have used the technique of dynamic laser scattering to measure sperm motility and to study the structure of cervical mucus by analyzing the molecular dynamics of the mucus. The correlation of the two is evaluated by a modified Kremer test. The clinical significance of the test is quantitatively expressed by the penetration factor and the sperm-mucus interaction coefficient, which are derived from theory of transport phenomena.


Swimming Speed Cervical Mucus Antisperm Antibody Sperm Penetration Mucus Sample 
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Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • Wylie I. Lee
    • 1
  1. 1.Center for Bioengineering and Department of Biological StructureUniversity of WashingtonSeattleUSA

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