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Cell Growth pp 171–218Cite as

Condensed Chromatin: Species-Specificity, Tissue-Specificity, and Cell Cycle-Specificity, as Monitored by Scanning Cytometry

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Part of the book series: NATO Advanced Study Institutes Series ((NSSA,volume 38))

Abstract

The main point of this essay will be the question, how condensed chromatin can be interpreted in terms of its molecular determinants and its functional significance, in different taxa. I shall not discuss the lower levels of DNA packaging up to the quaternary structure (or solenoid) in details, as this was recently done by several authors (1–5). It will be shown that condensed chromatin at the quinternary level is species-specific in plants and probably insects, while it is tissue-specific in vertebrates. In all cases, the degree of condensation considerably varies during the cell cycle. The evolution of condensed chromatin including heterochromatin will be discussed. Its possible role in the control of gene activity, determination, differentiation, and morphogenesis is suggested and illustrated by hiterto unpublished quantitative data.

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  1. Department of Biology, University of Kaiserslautern, 6750, Kaiserslautern, Federal Republic of Germany

    W. Nagl

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  1. Health Sciences Center, Department of Biochemistry and Physiology, Temple University, Philadelphia, Pennsylvania, 19140, USA

    Claudio Nicolini

  2. National Research Council, Genoa, Italy

    Claudio Nicolini

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Nagl, W. (1982). Condensed Chromatin: Species-Specificity, Tissue-Specificity, and Cell Cycle-Specificity, as Monitored by Scanning Cytometry. In: Nicolini, C. (eds) Cell Growth. NATO Advanced Study Institutes Series, vol 38. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4046-1_9

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