Antibiotic Resistance of Gram Negative Bacteria in Mexico: Relationship to Drug Consumption
The selection of bacterial strains resistant to antibiotics is closely linked to the usage of antimicrobial agents 1,2,3. In Japan during 1951, six years after the clinical introduction of sulfanilamide, approximately 80% of the strains of Shigella studied were found resistant to it, whereas in 1949 only 10% were resistant. Similarly, increases in the incidence of drug resistant microorganisms have been reported in Great Britain4, the United States5, the Netherlands6 and other countries1,7. In addition to the increase in the percentage of strains resistant to individual antibiotics, multiple resistant strains have been isolated with greater frequency as the age of antibiotherapy grows older4,7′8′9. In Mexico, Olarte and co-workers10,11 have reported the incidence of resistance to antibiotics in strains of Shigella, Salmonella and enteropathogenic E. coli and they have noted an increase in the frequency of multiple resistant strains.
KeywordsAntimicrobial Agent Antibiotic Resistance Resistant Strain Drug Consumption Resistant Bacterium
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