Antibiotic Resistance of Gram Negative Bacteria in Mexico: Relationship to Drug Consumption

  • Yankel M. Kupersztoch-Portnoy


The selection of bacterial strains resistant to antibiotics is closely linked to the usage of antimicrobial agents 1,2,3. In Japan during 1951, six years after the clinical introduction of sulfanilamide, approximately 80% of the strains of Shigella studied were found resistant to it, whereas in 1949 only 10% were resistant. Similarly, increases in the incidence of drug resistant microorganisms have been reported in Great Britain4, the United States5, the Netherlands6 and other countries1,7. In addition to the increase in the percentage of strains resistant to individual antibiotics, multiple resistant strains have been isolated with greater frequency as the age of antibiotherapy grows older4,789. In Mexico, Olarte and co-workers10,11 have reported the incidence of resistance to antibiotics in strains of Shigella, Salmonella and enteropathogenic E. coli and they have noted an increase in the frequency of multiple resistant strains.


Antimicrobial Agent Antibiotic Resistance Resistant Strain Drug Consumption Resistant Bacterium 


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Copyright information

© Springer Science+Business Media New York 1981

Authors and Affiliations

  • Yankel M. Kupersztoch-Portnoy
    • 1
  1. 1.Departamento de Genética y Biologia Molecular, Centre de Investigación y de EstudiosAvanzados del I.P.N. ApartadoMéxico 14Mexico

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