Transposition of the Inverted Repeats of Tn5

  • Douglas E. Berg
  • Chihiro Sasakawa
  • Bernard J. Hirschel
  • Lorraine Johnsrud
  • Lyn McDivitt
  • Carol Egner
  • Rajani Ramabhadran


The defining characteristic of bacterial transposons is their ability to move to new loci in the absence of extensive DNA sequence homology. Some, designated IS elements, contain only the genes and sites necessary for their own transposition; other transposons are composites of genes necessary for transposition and genes for auxiliary traits (such as antibiotic resistance or virulence)1. Although the mechanism of transposition is unknown, plausible models involving breakage and reunion2 or replication3,4 have been proposed.


Cold Spring Harbor Inverted Repeat Direct Repeat Tetr Gene Inverted Orientation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1981

Authors and Affiliations

  • Douglas E. Berg
    • 1
  • Chihiro Sasakawa
    • 1
  • Bernard J. Hirschel
    • 1
  • Lorraine Johnsrud
    • 1
  • Lyn McDivitt
    • 1
  • Carol Egner
    • 1
  • Rajani Ramabhadran
    • 1
  1. 1.Departments of Microbiology and Immunology and of GeneticsWashington University Medical SchoolSt. LouisUSA

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