Mechanisms of Plasmid-Determined Heavy Metal Resistances

  • Simon Silver


Many plasmids of both Gram negative and Gram positive bacteria have genes determining resistances to a wide range of toxic inorganic cations and anions, including ions of mercury (and organ-omercurials), cadmium (in Gram positives only), arsenic, antimony, bismuth, chromium, silver and tellurium. Three years ago, we reviewed the available information on the physiological and biochemical bases of these resistances, as well as the genetic structures that govern them (Summers and Silver, 1978). Here I will try to summarize both the overall picture and newer findings.


Heavy Metal Resistance Arsenate Resistance Silver Sulfadiazine Mercuric Reductase Phenyl Mercury 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1981

Authors and Affiliations

  • Simon Silver
    • 1
  1. 1.Department of BiologyWashington UniversitySt. LouisUSA

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