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Regulation of Yeast Alcohol Dehydrogenase Isozymes

  • Christopher Wills
  • Paul Kratofil
  • Tracy Martin
Part of the Basic Life Sciences book series

Abstract

The two major alcohol dehydrogenases of yeast are coded by separate nuclear genes, and show 95% amino acid homology. Nonetheless, the “constitutive” ADH, ADH-I, preferentially catalyzes the reaction acetaldehyde → ethanol, and the inducible ADH, ADH-II, preferentially catalyzes the reverse reaction. Linked and non-linked mutants rendering ADH-II constitutive have been isolated by Michael Ciriacy. An understanding of the regulation of these isozymes would greatly enhance our ability to control and understand the process of fermentation, and to isolate further regulatory mutants.

Keywords

Yeast Extract High Glucose Minimal Medium Complete Medium Alcohol Dehydrogenase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • Christopher Wills
    • 1
  • Paul Kratofil
    • 1
  • Tracy Martin
    • 1
  1. 1.Department of Biology C-016University of CaliforniaSan Diego, La JollaUSA

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