Mineralogical and Biochemical Analysis of Lung Washing Fluid from Patients Exposed to Asbestos

  • Jean Bignon
  • Marie-Claude Jaurand
  • Patrick Sebastien
Part of the Ettore Majorana International Science Series book series (EMISS, volume 6)


Recently, it has been shown in the baboon that broncho-alveolar lavage (BAL) is an efficient procedure for the recovery of radioactive particles deposited in the intra-alveolar compartment (1). For this reason, a prospective study was decided in order to investigate the possibility of assessing by means of this technique, the asbestos fiber content in the alveolar spaces of the human lung. The asbestos fibers recovered by BAL were quantitatively and qualitatively studied in order to see if this technique can help in the diagnosis of asbestos related diseases and if the fibers recovered are valuable indicators compared to sputum of past asbestos exposure and/of parenchymal asbestos burden.


Alveolar Macrophage Sputum Sample Alveolar Space Asbestos Exposure Asbestos Fiber 
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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Jean Bignon
    • 1
  • Marie-Claude Jaurand
    • 1
  • Patrick Sebastien
    • 1
  1. 1.Service de PneumologieERA CNRS et LEPICréteil cedexFrance

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