Acidic Amino Acids as Excitatory Transmitters

  • Carl W. Cotman


Some of the most important and exciting discoveries over these last few years have come from the identification and study of neurotransmitters. There are many new candidates, new regulatory mechanisms and new findings on the pathways which employ known transmitters. Curiously, though, most of the clearly identified neurotransmitters are inhibitory. Little is known about the excitatory pathways except that glutamate and aspartate are the major transmitter candidates for most excitatory pathways. The possibility that these amino acids might be transmitters was raised almost twenty five years ago.


Dentate Gyrus Molecular Layer Mossy Fiber Kainic Acid Acidic Amino Acid 
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Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • Carl W. Cotman
    • 1
  1. 1.University of California, IrvineIrvineUSA

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