Brain Clathrin: A Study of Its Properties

  • Saul Puszkin
  • Kenan Haver
  • William Schook


In 1968, Puszkin, Berl and coworkers reported the presence of contractile proteins in whole brain (1). Subsequent work showed the presence of contractile proteins in nerve-endings (2,3,4). The properties of various contractile proteins found in brain tissue resembled, to a large extent, those from muscle tissue (2,4). As a result, it was proposed that contractile activities are involved in neurotransmitter release (5). With the advantage of sodium dodecyl sulfate polyacrylamide gel electrophoresis as a procedure for distinguishing and comparing the size of various proteins, many researchers working with other tissues or cells began to report the presence and involvement of contractile proteins in motility-related cell functions (6).


Synaptic Vesicle DEAE Cellulose Contractile Protein Actin Stress Fiber Coated Vesicle 


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Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • Saul Puszkin
    • 1
  • Kenan Haver
    • 1
  • William Schook
    • 1
  1. 1.The Department of PathologyMount Sinai School of Medicine of the City University of New YorkNew YorkUSA

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