The term porphyria refers to a group of diseases, each with characteristic manifestations, that have in common excessive excretion of one or more porphyrins, porphyrinogens, and/or porphyrin precursors in the urine and/ or feces. The term porphyrinuria refers to porphyrins appearing in the urine and is thus a sign rather than a disease. Classification of these disorders is not entirely satisfactory, but most commonly they are separated into two general groups. The first is erythropoietic porphyria, a blood disorder in which excessive quantities of porphyrins are accumulated in the normoblasts and erythrocytes, the blood forming tissues. The second group is that of the hepatic porphyrias, which includes porphyria variegata, porphyria cutanea tarda, hereditary coproporphyria, and acute intermittent porphyria. It is this latter syndrome that has the most important psychiatric implications and, consequently, is the one most often described in the psychiatric literature.
KeywordsWilson Disease Copper Metabolism Porphyria Cutanea Tarda Intermittent Acute Porphyria Acute Intermittent Porphyria
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