Kerr Effects of Flexible Macromolecules

  • Robert L. Jernigan
  • Sanzo Miyazawa
Part of the NATO Advanced Study Institutes Series book series (NSSB, volume 64)


Detailed calculations of the effects of different conformations on the Kerr constant have become available only recently. These calculations can be utilized to evaluate the usefulness of Kerr constant measurements in characterizing configurations of macromolecules. Experimental scientists would like to know, in particular, if Kerr measurements are more sensitive to changes in conformation than other methods and for what types of molecules. These sensitivities must be judged against the results for more common characterization methods.


Dipole Moment Polarizability Tensor Optical Anisotropy Polarizability Anisotropy Bond Polarizability 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Applequist, J., Carl, J. R. and Fung, K.-K., 1972, An Atom Dipole Interaction Model for Molecular Polarizability. Application to Polyatomic Molecules and Determination of Atom Polarizabilities, J. Am. Chem. Soc., 94: 2952.CrossRefGoogle Scholar
  2. Brant, D. A., Miller, W. G. and Flory, P. J., 1967, Conformational Energy Estimates for Statistically Coiling Polypeptide Chains, J. Mol. Biol., 23: 47.CrossRefGoogle Scholar
  3. Buckingham, A. D. and Sutter, H., 1976, Gas Phase Measurements of the Kerr Effect in Some n-Alkanes and Cyclohexane, J. Chem. Phys., 64: 364.ADSCrossRefGoogle Scholar
  4. Bunn, C. W. and Daubeny, R. D. P., 1954, The Polarizabilities of Carbon-Carbon Bonds, Trans. Faraday Soc., 50: 1173.CrossRefGoogle Scholar
  5. Flory, P. J. and Jernigan, R. L., 1968, Kerr Effect in Polymer Chains, J. Chem. Phys., 48: 3823.ADSCrossRefGoogle Scholar
  6. Flory, P. J., 1969, “Statistical Mechanics of Chain Molecules”, Interscience, New York.Google Scholar
  7. Ingwall, R. T., Czurylo, E. A. and Flory, P. J., 1973, Kerr Constants of Amides and Peptides, Biopolymers, 12: 1137.CrossRefGoogle Scholar
  8. Ingwall, R. T. and Flory, P. J., 1972, Optical Anisotropy of Polypeptide Chains, Biopolymers, 11: 1527.CrossRefGoogle Scholar
  9. Ishikawa, T. and Nagai, K., 1971, Theoretical Interpretation of Kerr Constants of Polymer Chains. n-Alkanes, Poly(oxyethylene glycol)s, and Poly(oxyethylene dimethyl Ether)s, Polymer J., 2: 263.CrossRefGoogle Scholar
  10. Jernigan, R. L. and Flory, P. J., 1967, Optical Anisotropy of Chain Molecules. Theory of Depolarization of Scattered Light with Application to n-Alkanes, J. Chem. Phys., 47: 1999.ADSCrossRefGoogle Scholar
  11. Jernigan, R. L. and Thompson, D. S., 1976, Flexible Polymers, in: “Molecular Electro-Optics”, Part 1, C. T. O’Konski, ed.; Marcel Dekker, New York.Google Scholar
  12. Kelly, K. M., Patterson, G. D. and Tonelli, A. E., 1977, Kerr Effect Studies of the Poly(oxyethylenes), Macromolecules, 10: 859.ADSCrossRefGoogle Scholar
  13. Khanarian, G., 1980, The Kerr Effect of Aqueous Solutions, Thesis, Univ. of Sydney.Google Scholar
  14. Khanarian, G., Mack, P. and Moore, W. J., 1980, Optical Anisotropies of Amides and Peptides in Dioxane, in press.Google Scholar
  15. Ladanyi, B. M. and Keyes, T., 1979, Effect of Internal Fields on Depolarized Light Scattering from n-Alkane Gases, Molec. Phys., 37: 1809.Google Scholar
  16. Le Fevre, C. G. and Le Fevre, R. J. W., 1955, The Kerr Effect. Its Measurement and Application in Chemistry, Rev. Pure Appl. Chem., 5: 262.Google Scholar
  17. Le Fevre, R. J. W., 1965, Molecular Refractivity and Polarizability, in: “Advances in Physical Organic Chemistry”, Vol. 3, V. Gold, ed., Academic Press, London.Google Scholar
  18. Le Fevre, R. J. W., Orr, B. J. and Ritchie, G. L. D., 1966, Molecular Polarisability. The Anisotropic Electron Polarisability of Aliphatic C-C and C-H Bonds, J. Chem. Soc.(B), 1966: 273.Google Scholar
  19. Mark, J. E., 1974, The Use of Dipole Moments to Characterize Configurations of Chain Molecules, Acc. Chem. Res., 7: 218.CrossRefGoogle Scholar
  20. Meeten, G. H., 1968, Hyperpolarizability Contributions to Kerr Effect in Liquids, Trans. Faraday Soc., 64: 2267.CrossRefGoogle Scholar
  21. Mortensen, E. M., 1968, Polarizability of Molecules Considering Internal-Field Effects Using a Point Dipole Approximation, J. Chem. Phys., 49: 3732.ADSCrossRefGoogle Scholar
  22. Nagai, K. and Ishikawa, T., 1965, Internal Rotation and Kerr Effect in Polymer Molecules, J. Chem. Phys., 43: 4508.ADSCrossRefGoogle Scholar
  23. Patterson, G. D. and Flory, P. J., 1972, Depolarized Rayleigh Scattering and Mean-squared Optical Anisotropies of nAlkanes in Solution, J. Chem. Soc., Faraday Trans. II, 68: 1098.Google Scholar
  24. Poland, D. and Scheraga, H. A., 1970, “Theory of Helix-Coil Transitions in Biopolymers”, Academic Press, New York.Google Scholar
  25. Rowell, R. L. and Stein, R. S., 1967, The Internal Field and the Additivity of Bond Polarizabilities, J. Chem. Phys., 47: 2985.ADSCrossRefGoogle Scholar
  26. Saiz, E., Suter, U. W. and Flory, P. J., 1977, Optical Anisotropies of para-Halogenated Polystyrenes and Related Molecules, J. Chem. Soc., Trans. Faraday Soc. II, 73: 1538.Google Scholar
  27. Silberstein, 1917, Molecular Refractivity and Atomic Interaction, Phil. Mag., Ser. 6, 33:92; 1917, Molecular Refractivity and Atomic Interaction II, ibid, 33: 521.Google Scholar
  28. Stuart, H. A. and Kuster, R., 1962, Kerr-Konstanten von Flüssigkeiten in: “Landolt-BBrnstein Zahlenwerte und Funktionen”, 6th ed., Vol. II, Pt. 8, p. 849, Springer Verlag, Berlin.Google Scholar
  29. Tonelli, A. E., 1977, Possible Characterization of Homopolymer Configuration and Copolymer Sequence Distribution by Comparison of Measured and Calculated Molar Kerr Constants, Macromolecules, 10: 153.ADSCrossRefGoogle Scholar
  30. Zimm, B. H. and Bragg, J. K., 1959, Theory of the Phase Transition between Helix and Random Coil in Polypeptide Chains, J. Chem. Phys., 31: 526.ADSCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • Robert L. Jernigan
    • 1
  • Sanzo Miyazawa
    • 1
  1. 1.Laboratory of Theoretical Biology National Cancer InstituteNational Institutes of HealthBethesdaUSA

Personalised recommendations