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Analytical Studies on Biochemistry and Physiology of Perilymph (Guinea Pig)

  • F. Scheibe

Abstract

The genesis and the biochemical nature of perilymph (PL) — ultrafiltrate from the cochlear blood vessels or/and open influx of cerebrospinal fluid (CSF) -, and even more its metabolic function for the organ of Corti, are basic questions of the biochemistry and the physiology of PL which have not been solved completely yet (Schindler, 1965; Gershbein et al., 1974; Lawrence, 1974; Schnieder, 1974; Jung, 1975, 1979; Lawrence et al., 1975; Kellerhals, 1976; Scheibe et al., 1977; Cabezudo, 1978; Kommos and Giebel, 1978). A contribution to solve this problem is a comprehensive biochemical comparison between PL, CSF and blood plasma. The analytical data available in the literature are insufficient to compare the chemical compositions of these fluids exactly.

Keywords

Blood Plasma Basilar Membrane Pyruvate Lactate Biochemical Nature High Molecular Component 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Bergmann, K., Haupt, H., Scheibe, F. and Rogge, I., 1979, Der Verschluss des Aquaeductus cochleae für Perilymphuntersuchungen am Meershweinchen, Arch. Otorhinolaryngol., 224: 257–266.PubMedCrossRefGoogle Scholar
  2. Cabezudo, L. M., 1978, The ultrastructure of the basilar membrane in the cat, Acta Otolaryngol., 86: 160–175.PubMedCrossRefGoogle Scholar
  3. Giebel, W. and Scheibe, F., Zur mikroflammenphotometrischen Elektrolytbestimmung in Innenohrflussigkeiten, in preparation.Google Scholar
  4. Gershbein, L. L., Manshio, D. T. and Shurrager, P. S., 1976, Biochemical parameters of guinea pig perilymph sampled according to scala and following sound presentation, Enviroment. Health Perspect., Vol., 157–164.Google Scholar
  5. Haupt, H., Bergmann, K. and Scheibe, F., 1979, Zur Gesamtaktivität der Laktatdehydrogenase von Perilymphe, Plasma und Liquor cerebrospinalis normaler und schallbelasteter Meerschweinchen, in; “Cochlea-Forschung 77”, H. Jakobi and K.-D. Kühl, eds., Martin-Luther-Universität, Halle (Saale).Google Scholar
  6. Jung, W. K., 1975, Zur Resorptionskinetik der cochleären Perilymphe, gemessen mit Radionucliden nach minimaler Störung, Arch. Otorhinolaryngol., 211: 113–127.PubMedCrossRefGoogle Scholar
  7. Jung, W. K., 1979, Results in evaluating cochlear kinetics of carbon-14 labelled metabolites, Revue de Laryngologie, 100: 207–214.Google Scholar
  8. Kellerhals, B., 1976, Quantitative assessment of perilymph sources, ORL 38: 193–197.PubMedCrossRefGoogle Scholar
  9. Kommoss, J. and Giebel, W., 1978, Die Ausbreitung loslicher Substanzen nach Applikation in die Cisterna cerebellomedularis, Arch. Otorhinolaryngol., 221: 67–76.PubMedCrossRefGoogle Scholar
  10. Lawrence, M., 1976, Direct visualization of living organ of Corti and studies of its extracellular fluids, Laryngoscope, 84: 1767–1776.CrossRefGoogle Scholar
  11. Lawrence, M., Nuttal, A. L. and Burgio, P. A., 1975, Cochlear potentials and oxygen associated with hypoxia, Ann. Otol., 84: 499–508.Google Scholar
  12. Scheibe, F., Haupt, H. and Hache, U., 1976, Vergleichende Untersuchungen der Laktatkonzentration von Perilymphe, Blut und Liquor cerebrospinalis normaler und schallbelasteter Meerschweinchen, Arch. Otorhinolaryngol., 214: 19–25.PubMedCrossRefGoogle Scholar
  13. Scheibe, F., Haupt, H., Hache, U. and Bergmann, K., 1977, Analytischer Vergleich einiger chemischer Bestandteile in Perilymphe, Liquor cerebrospinalis und Blut des Meerschweinchens, in: “Inner Ear Biology”, M. Portmann and J.-M. Aran, eds., INSERM, Paris.Google Scholar
  14. Scheibe, F., Hache, U. and Haupt, H., 1979, Zur Laktat- und Pyruvat-konzentration von Perilymphe, Blut und Liquor cerebrospinalis des Meerschweinchens, in: “Cochlea-Forschung 77”, H. Jakobi and K.-D. Kuhl, eds., Martin-Luther-Universität, Halle (Saale).Google Scholar
  15. Schindler, K., 1965, Perilymphe als Ultrafiltrat des Serums, Arch. Ohr.-, Nas.- u. Kehlk.-Heilk. 185: 586–592.CrossRefGoogle Scholar
  16. Schnieder, E.-A., 1974, A contribution to the physiology of the perilymph. Part I: The origins of perilymph., Ann. Otol., 83: 76–83.Google Scholar

Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • F. Scheibe
    • 1
  1. 1.ENT ClinicHumboldt University of BerlinBerlinGermany

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