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The Dynamics of pO2-Changes in the Perilymphatic Perfusate of the Guinea-Pig Cochlea Depending on the Metabolism

  • E.-J. Haberland
  • K.-D. Kuhl
  • P. Lotz

Abstract

We perfused the perilymphatic space of the guinea-pig cochlea with an artificial perilymph of a balanced ionic composition. The indicators for the metabolic situation of the cochlea are the cochlear microphonics (CM), the oxygen partial pressure and the concentration of different metabolites of the perfused artificial perilymph. CM and oxygen tension are recorded simultaneously. The fractioned perfusate drops are examined later biochemically. The animal is narcotized by urethane, relaxed and machine-made respired. Changes of the metabolic status are induced by respiring with chosen gas compositions or by admixtures to the artificial perilymph before perfusion.

Keywords

Oxygen Partial Pressure Oxygen Tension Perfusion Rate Cochlear Microphonic Metabolic Situation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Reference

  1. Haberland, E.-J., Kuhl, K.-D. and Lotz, P., 1977, Zu Problemen der perilymphatischen Cochleaperfusion, Wiss. Beitr. Martin-Luther-Univ. Halle, 43: 123–128.Google Scholar

Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • E.-J. Haberland
    • 1
  • K.-D. Kuhl
    • 1
  • P. Lotz
    • 1
  1. 1.Department of Otolaryngology, Medical SchoolMartin-Luther UniversityHalleGermany

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