Advertisement

The Responses of Hair Cells to Low Frequency Tones and Their Relationship to the Extracellular Receptor Potentials and Sound Pressure Level in the Guinea Pig Cochlea

  • I. J. Russell
  • P. M. Sellick

Abstract

This paper is concerned with a description of the receptor potential recorded intraeellularly from inner hair cells in the basal turn of the guinea pig cochlea. It includes a discussion of the special properties which permit the responses of hair cells to high frequency auditory stimulation to be transmitted to auditory nerve fibres. Finally, the intracellularly recorded receptor potentials from inner hair cells are compared with the extracellularly recorded cochlear microphonic from the scala tympani and sound pressure, measured at the tympanic membrane, in response to low frequency tones. These measurements form a basis for comparing the way in which the stereocilia of inner and outer hair cells are mechanically coupled to the overlying tectorial membrane.

Keywords

Hair Cell Tympanic Membrane Receptor Potential Outer Hair Cell Basilar Membrane 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Dallos, P., 1970, Low frequency auditory characteristics: species dependence, J. Acoust. Soc. Am., 48: 489–499.PubMedCrossRefGoogle Scholar
  2. Dallos, P., 1973, Cochlear potentials and cochlear mechanics, in: “Basic Mechanisms in Hearing”, A. Møller, ed. Academic Press, New York, London.Google Scholar
  3. Dallos, P. and Cheatham, M. A., 1976, Production of cochlear potentials by inner and outer hair cells, J. Acoust. Soc. Am., 60: 510–512.PubMedCrossRefGoogle Scholar
  4. Dallos, P., Bilione, M. C., Durrant, J. D., Wang, C-y. and Raynor, S., 1972, Cochlear inner and outer hair cells: functional differences, Science 177: 356–358.PubMedCrossRefGoogle Scholar
  5. Engström, H. and Engström, B., 1978, Structure of the hairs on cochlear sensory cells, Hearing Res., 1: 49–66.CrossRefGoogle Scholar
  6. Fettiplace, R. and Crawford, A. C., 1978, The coding of sound pressure and frequency in cochlear hair cells of the terrapin, Proc. R. Soc. Lond. B, 203: 209–218.PubMedCrossRefGoogle Scholar
  7. Flock, A. and Russell, I J., 1973, Efferent nerve fibres: postsynaptic action on hair cells, Nature, 243: 89–91.CrossRefGoogle Scholar
  8. Flock, A. and Russell, I. J., 1976, Inhibition by efferent nerve fibres: action on hair cells and afferent synaptic transmission in the lateral line canal organ of the Burbot Lota lota, J. Physiol., 257: 45–62.PubMedGoogle Scholar
  9. Furukawa, T. and Ishii, Y., 1967, Neurophysiological studies on hearing in goldfish, J. Neurophys., 30: 1377–1403.Google Scholar
  10. Hudspeth, A. J. and Corey, D. P., 1977, Sensitivity, polarity and conductance changes in the response of vertebrate hair cells to controlled mechanical stimuli, Proc. Natl. Acad. Sci., 74: 2407–2411.PubMedCrossRefGoogle Scholar
  11. Katz, B., 1969, “The Release of Neural Transmitter Substances”, Liverpool University Press, Liverpool.Google Scholar
  12. Kimura, R. S., 1966, Hairs of the cochlear sensory cells and their attachment to the tectorial membrane, Acta Otolaryngol., 61: 55–63.PubMedCrossRefGoogle Scholar
  13. Lim, D. J., 1972, Fine morphology of the tectorial membrane, Arch. Otolaryngol. 96: 199–215.PubMedCrossRefGoogle Scholar
  14. Rose, J. E., Brugge, J. F., Anderson, D. J. and Hind, J. E., 1968, Patterns of activity in single auditory nerve fibres of the squirrel monkey, in: “Hearing Mechanisms in Vertebrates”, A. V. S. de Reuck and J. Knight, eds., Churchill, London.Google Scholar
  15. Russell, I. J., 1980, The responses of vertebrate hair cells to mechanical stimulation, in: “Neurones without Impulses”, A. Roberts and B. Bush, eds. Cambridge University Press, in press.Google Scholar
  16. Russell, I. J. and Sellick, P. M., 1977, Tuning properties of cochlear hair cells, Nature, 267: 858–860.PubMedCrossRefGoogle Scholar
  17. Russell, I. J. and Sellick, P. M., 1978, Intracellular studies of hair cells in the mammalian cochlea, J. Physiol., 284: 261–290.PubMedGoogle Scholar
  18. Sand, O., Ozawa, S. and Hagiwara, S., 1975, Electrical and mechanical stimulation of hair cells in the mudpuppy, J. Comp. Physiol., 102: 13–26.CrossRefGoogle Scholar
  19. Sellick, P. M. and Russell, I. J., 1980, The responses of inner hair cells to basilar membrane velocity during low frequency auditory stimulation in the guinea pig cochlea, Hearing Res., in press.Google Scholar
  20. Spoendlin, H., 1978, The afferent innervation of the cochlea, in: “Evoked Electrical Activity in the Auditory Nervous System”, R. F. Naunton and C. Fernandez, eds., Academic Press, New York, San Francisco, London.Google Scholar
  21. Tanaka, Y., Asanuma, A. and Yanagisawa, K., 1980, Potentials of outer hair cells and their membrane properties in cationic environments, Hearing Res., in press.Google Scholar

Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • I. J. Russell
    • 1
  • P. M. Sellick
    • 2
  1. 1.Ethology and Neurophysiology Group, School of Biological SciencesThe University of SussexFalmer, Brighton, SussexUK
  2. 2.Department of PhysiologyUniversity of Western AustraliaNedlandsAustralia

Personalised recommendations