Abstract
Around 15 years ago the first metabolic steps in the inactivation of prostaglandins were elucidated. It was demonstrated that PGs of the E and F type were extensively taken up by many organs and tissues in the body (see (1) and references therein), mainly by the liver, kidney and lungs, and were inactivated by a few metabolic steps.
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Granström, E. (1981). Metabolism of Prostaglandins and Thromboxanes. In: Berti, F., Velo, G.P. (eds) The Prostaglandin System. NATO Advanced Study Institutes Series. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3896-3_4
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