Serotonin pp 739-752 | Cite as

Studies of CSF 5-HIAA in Depression and Suicidal Behaviour

  • Marie Åsberg
  • Lil Träskman
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 133)


A role for serotonin in the development of depressive illness has been suggested since the sixties (e.g. by Lapin and Oxenkrug 1969). Evidence for the importance of the neurotransmitter has largely been indirect and drawn, inter al., from pharmacological data. Many antidepressant treatments have effects on serotonin neurons. The monoamine oxidase inhibitors and some of the tricyclic antidepressants potentiate serotonergic functions, and recently this was found to be true also for convulsive treatments (Green and Grahame-Smith 1978).


Depressed Patient Suicidal Behaviour Depressive Illness Serotonin Neuron Monoamine Metabolite 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • Marie Åsberg
    • 1
  • Lil Träskman
    • 1
  1. 1.Department of Psychiatry, Karolinska instituteKarolinska hospitalStockholm 60Sweden

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