Serotonin pp 375-390 | Cite as

The Action of Serotonin in the Rat Hippocampus

  • Menahem Segal
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 133)


Serotonin (5HT) is one of the main monoamine neurotransmitters in the brain. Its biochemistry and pharmacology (Bloom et al., 1972; Costa et al., 1974; Weight and Salmoiraghi, 1968; Bennett and Snyder, 1976; Nelson et al., 1978), brain distribution (Azmitia, 1978; Azmitia and Segal, 1978; Conrad et al., 1974; Bobillier et al., 1976; Moore and Halaris, 1975; Segal and Landis, 1974) and functions (Akil and Liebeskind, 1975; Jacobs et al., 1974; Jouvet, 1969; Lorens and Yunger, 1974) have been the subject of numerous investigations in the past decade. Compared with the wealth of information gathered in these disciplines, relatively little was known until recently about the postsynaptic action of 5HT and the mechanisms by which it exerts its overt behavioral effects.


Kainic Acid Dorsal Raphe Nucleus Excitatory Response Stratum Radiatum Schaffer Collateral 


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Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • Menahem Segal
    • 1
  1. 1.Isotope DepartmentWeizmann Institute of ScienceRehovotIsrael

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