DNA Repair Pathways
Our knowledge about DNA repair mechanisms in mammalian cells is reviewed. Ways of measuring excision repair are summarized, and various modes of excision repair are described in terms of mechanisms that yield patch sizes of 0, 1, a few (short patch), and many (long patch) bases. The biological and molecular ways of measuring the effects of replication on a damaged template are presented, as are various models of postreplication repair.
KeywordsExcision Repair Nucleotide Excision Repair Pyrimidine Dimer Thymine Dimer Dimethyl Nitrosamine
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