Influence of Barbiturates, Hypothermia and Hemodilution on Post-Ischemic Metabolism and Functional Recovery Following Cerebro-Circulatory Arrest in Cats

  • W. van den Kerckhoff
  • Y. Matsuoka
  • W. Paschen
  • K.-A. Hossmann


Increasing evidence provided by several laboratories over the past years has drawn attention to the fact that recovery of the brain following a period of cerebro-circulatory arrest depends not only on the duration of ischemia but equally on post-ischemic events, above all the quality of post-ischermic recirculation (1, 15, 26). Two phases are particularly critical: the period immediately after ischemia, when blood flow is restored, and a later period when spontaneous electro-cortical activity begins to recover.


Cerebral Blood Flow Prolonged Ischemia Electrocortical Activity Anaerobic Glucose Metabolism Electrophysiological Recovery 
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Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • W. van den Kerckhoff
    • 1
  • Y. Matsuoka
    • 1
  • W. Paschen
    • 1
  • K.-A. Hossmann
    • 1
  1. 1.Forschungsstelle für HirnkreislaufforschungMax-Planck-Institut für HirnforschungKöln (Merheim)West Germany

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