Role of Prostaglandins in Leydig-Cell Stimulation by hCG and Leydig-Cell Function

  • F. Haour
  • J. Mather
  • B. Bizzini-Kouznetzova
  • F. Dray
Part of the Biochemical Endocrinology book series (BIOEND)


In many different cell types, prostaglandins have the ability to modify hormone action (Shio et al., 1971), an effect known to be correlated with changes in cyclic AMP (cAMP) levels. In the restricted case of steroid-producing cells, as found in ovarian and testicular tissues, numerous data indicate that prostaglandins are directly involved in the mechanism of luteinizing hormone (LH)-human chorionic gondadotropin (hCG) action and in post-cAMP events (Phariss and Behrman, 1973; Kuehl et al., 1970; Kuehl, 1974; Cenedella, 1975; Samuelson et al., 1978).


Luteinizing Hormone Leydig Cell Corpus Luteum Prostaglandin Synthesis cAMP Accumulation 


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Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • F. Haour
    • 1
  • J. Mather
    • 2
  • B. Bizzini-Kouznetzova
    • 3
  • F. Dray
    • 3
  1. 1.Hôpital DebrousseINSERM U 162LyonFrance
  2. 2.Center for Biomedical Research, The Population CouncilThe Rockefeller UniversityNew YorkUSA
  3. 3.Institut PasteurINSERM FRA 8ParisFrance

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