Control of Gonadotropin and Prolactin Secretion in Rhesus Monkeys and Rodents
Since the pioneering work of Moore and Price (1932), it has been well documented that the ovary and anterior pituitary gland (AP) exist in a dynamic equilibrium. Simply stated, the AP secretes the gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH). These glycoproteins bind to the ovary at specific receptor sites and stimulate the synthesis and secretion of ovarian steroids. These steroids travel from the ovary, through the peripheral circulation, to the AP and the hypothalamus (the area of the brain that regulates the secretions of the AP) to stimulate or inhibit further gonadotropin secretion.
KeywordsLuteinizing Hormone Rhesus Monkey Luteal Phase Estrous Cycle Anterior Pituitary
Unable to display preview. Download preview PDF.
- Batta, S.K., and Channing, C.P., 1980, Demonstración de una inhibina en el liquido follicular humano y su posible papel en la disfunción ovarica, in: Advances en Obstetricia y Ginecologigia, Vol. 6 (J. Gonzales-Merlo, J. Iglesiar-Guiu, and 1. Burzaco, eds.), pp. 125–134, Salvat, Barcelona.Google Scholar
- Bogdanove, E.M., 1964, The role of the brain in the regulation of pituitary gonadotropin secretion, Vitam. Horm. (N.Y.) 22: 205.Google Scholar
- Chari, S., Hopkinson, C.R.N., Duame, D., and Sturm, G., 1979, Purification of “inhibin” from human ovarian follicular fluid, Acta Endocrinol. 90: 157.Google Scholar
- DePaulo, L.V., Shander, D., Wise, P.M., Channing, C.P., and Barraclough, C.A., 1979, Evidence for ovarian secretion of “inhibin,” Fed. Proc. Fed. Am. Soc. Exp. Biol. (abstract 3985 ).Google Scholar
- Greenwald, G.S., 1974, Role of follicle-stimulating hormone and luteinizing hormone in follicular development and ovulation, in: Handbook of Physiology, Section 7, Vol. IV ( R.O. Greep and E.B. Astwood, eds.), pp. 293–323, Williams and Wilkins, Baltimore.Google Scholar
- Knobil, E., 1974, On the control of gonadotropin secretion in the rhesus monkey, Recent Prog. Horm. Res. 30: 1.Google Scholar
- Neill, J.D., Frawley, L.S., Plotsky, P., and Tindall, G.T., 1978, Regulation of prolactin secretion by dopamine in the rhesus monkey, Society for the Study of Reproduction Annual Meeting, Abstract 113.Google Scholar
- Resko, J.A., Norman, R.L., Niswender, G.D., and Spies, H.G., 1974, The relationshipGoogle Scholar
- between progestins and gonadotropins during the late luteal phase of the menstrual cycle in rhesus monkeys, Endocrinology 94:128.Google Scholar
- Schwartz, N.B., 1969, A model for the regulation of ovulation in the rat, Recent Prog. Horm. Res. 25: 1.Google Scholar