Gallbladder Diseases

  • Martin H. Floch
Part of the Topics in Gastroenterology book series (TGEN)


The gallbladder is the site of concentration of biliary secretions so that hepatic bile is converted to gallbladder bile. Due to the action of cholecystokininpancreozymin (CCK-PZ) and complex neurogenic reflexes, it contracts during feeding. The major stimuli of CCK-PZ are fat-containing foods. When they enter the duodenum, the hormone is secreted and the gallbladder contracts, secreting its contents through the common duct into the duodenal sweep, where it mixes with the bolus of food to help form micelles for absorption of fats and cholesterol. Postcholecystectomy patients secrete bile at a continuous rate, but they adapt so that there is adequate secretion of bile during feeding, preventing malabsorption. The gallbladder and its contents and functions are described in more detail in Chapter 1.


Bile Acid Bile Salt Chenodeoxycholic Acid Gallbladder Disease Gallstone Formation 
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Copyright information

© Plenum Publishing Corporation 1981

Authors and Affiliations

  • Martin H. Floch
    • 1
    • 2
  1. 1.Yale University School of MedicineUSA
  2. 2.Department of Medicine, Section of Gastroenterology and NutritionNorwalk HospitalUSA

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