Interspecies MHS Relationships Studied by Serological and Cellular Cross-Reactions

  • P. Ivànyi


The major histocompatibility system (MHS) is an interrelated complex of genes located on a phylogenetically conserved chromosomal region involved in immunological processes. The gene products are transplantation antigens, Ia antigens, and complement factors. The precise relationship of these molecules to the multiple functions associated (in physiology and pathology) with the MHS is still unclear. It is characteristic of the MHS that an extensive series of alleles (a high degree of polymorphism) occurs at the individual gene loci.


Tissue Antigen Rabbit Seron Transplantation Antigen Individual Seron Heterophile Antibody 
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Copyright information

© Springer Science+Business Media New York 1981

Authors and Affiliations

  • P. Ivànyi
    • 1
  1. 1.Central Laboratory, Netherlands Red Cross Blood Transfusion Service; Laboratory of Experimental and Clinical ImmunologyUniversity of AmsterdamAmsterdamThe Netherlands

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