Antigenic Products of the HLA-D Region

  • B. G. Solheim
  • D. Albrechtsen
  • E. Thorsby


A multitude of different cell-membrane alloantigens, complement factors, and components that may have important functions in the regulation of the immune response are controlled by the HLA genetic complex of chromosome 6 (W.F. Bodmer et al., 1978). In this chapter, the identification, structure, tissue distribution, and clinical importance of the HLA-D-region antigens are discussed (see also Thorsby et al., 1978). The HLA-D determinants are recognized by cellular techniques, while the HLA-D-related (DR) antigens are detected by serological methods. The relationship between the HLA-D determinants and HLA-DR antigens is also discussed.


Tissue Antigen Dermatitis Herpetiformis Antigenic Product Mixed Leukocyte Culture Plan Immunization 
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Copyright information

© Springer Science+Business Media New York 1981

Authors and Affiliations

  • B. G. Solheim
    • 1
  • D. Albrechtsen
    • 1
  • E. Thorsby
    • 1
  1. 1.The Tissue Typing LaboratoryRiks-hospitalet (The National Hospital)OsloNorway

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