Abstract
The transport of solutes and water between blood and brain tissue depends on such things as the rate of tissue blood flow, the permeabilities of the capillary and cellular membranes, and the sizes of the various tissue distribution spaces. In some pathologic situations, the primary cause of the lesion is the interruption of the normal operation of one or more of these transport components, for example, local tissue blood flow in stroke. In other conditions, the presence of the initial pathologic disturbance subsequently affects the movements of materials within the system, for instance, the development of edema in and around a tumor site.
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© 1980 Plenum Press, New York
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Blasberg, R.G., Gazendam, J., Patlak, C.S., Shapiro, W.S., Fenstermacher, J.D. (1980). Changes in Blood-Brain Transfer Parameters Induced by Hyperosmolar Intracarotid Infusion and by Metastatic Tumor Growth. In: Eisenberg, H.M., Suddith, R.L. (eds) The Cerebral Microvasculature. Advances in Experimental Medicine and Biology, vol 131. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3752-2_24
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DOI: https://doi.org/10.1007/978-1-4684-3752-2_24
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