Preparation and Characterization of Metal Oxide-Coated Supports for Oxidase Enzymes

  • B. R. Allen
  • D. J. Fink


In our early studies on the immobilization of L-amino acid oxidase (1), we co-immobilized catalase in order to decompose H2O2 that is produced in the primary reaction of L-amino acids to α-keto acids. The catalase activity was lost relatively rapidly, leading to a loss in oxidase activity. This problem led us to investigate other methods for achieving in situ degradation of H2O2 by non-enzymatic catalysis. Similar approaches to this problem have also been investigated recently using glucose oxidase (2–4) and D-amino acid oxidase (5) systems.


Manganese Oxide Cobalt Oxide Acid Oxidase Oxidase Enzyme Ruthenium Oxide 
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Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • B. R. Allen
    • 1
  • D. J. Fink
    • 1
  1. 1.Battelle Columbus LaboratoriesColumbusUSA

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