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Continuous Deacetylation of Cephalosporins

  • Jan Konecny
  • Meinrad Sieber

Abstract

The non-specific acetyl esterase from B. subtilis (AT 6633) has been immobilized on several carriers represeating a wide range of binding capacities, morphologies and physical and mechanical properties (1,2,3). The relative merits of batch and continuous reactors for the deacetylation of cephalosporins with the enzyme have been discussed (3).

Keywords

Space Velocity Microbial Matter Free Enzyme Column Performance Column Efficiency 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    KONECNY, J. & VOSER, W. Biochim. Biophys. Acta 485: 367, 1977.Google Scholar
  2. 2.
    KONECNY, J. Survey of Progress in Chemistry 8; 195, 1977.Google Scholar
  3. 3.
    KONECNY, J. & SIEBER, M. Biotechnology Letters 1(2): 87, 1979.CrossRefGoogle Scholar
  4. 4.
    KONECNY, J. & SLANICKA, J. Biochim. Biophys. Acta 403: 573, 1975.Google Scholar
  5. 5.
    KONECNY, J., FELBER, E. & GRÜNER, J. J. Antibiotics 26: 135, 1973.Google Scholar
  6. 6.
    YAMANA, T. & TSUJI, A. J. Pharm. Sci. 65: 1563, 1976.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • Jan Konecny
    • 1
  • Meinrad Sieber
    • 1
  1. 1.Pharmaceuticals DivisionCIBA-GEIGY LimitedBaselSwitzerland

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