Advertisement

Immobilized Enzymes for Medical Application

  • E. I. Chazov
  • V. N. Smirnov
  • V. P. Torchilin
  • I. M. Tereshin
  • B. V. Moskvichev

Abstract

The basic problems researchers deal with on the elaborattion of novel enzyme preparations are:
  • increase of the enzyme stability in vivo realtive to the action of endogenous proteinases, inhibitors and antibodies;

  • stability increase on storage;

  • decrease of the organism response to foreign protein, and namely decrease of their immunogenicity, antigenicity, allergenicity potential and toxicity;

  • decrease of the enzyme preparation dose;

  • prolongation of the enzyme action or ensurance of the enzyme preparations pharmacokinetics.

Keywords

Immobilize Enzyme Enzyme Preparation Native Enzyme Foreign Protein Covalent Immobilization 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • E. I. Chazov
  • V. N. Smirnov
  • V. P. Torchilin
  • I. M. Tereshin
  • B. V. Moskvichev

There are no affiliations available

Personalised recommendations