Abstract
It has been proposed that Bacillus licheniformis penicillinase production depends on a phospholipoprotein intermediate and an exo-enzyme releasing protease. Studies using cerulenin, a lipid synthesis inhibitor, and quinacrine, a protease inhibitor, which are presumed to interfere with phospholipoprotein synthesis and the releasing protease respectively, with this penicillinase and other exo-proteins suggest a common export mechanism for proteins. However, recent findings on the nature of the exo-penicillinase precursor cast doubt on this mechanism and its ubiquity.
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© 1980 Plenum Press, New York
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Pepper, E.A., Melling, J., Berkeley, R.C.W. (1980). Bacterial Exo-Enzyme and Exo-Toxin Export. In: Weetall, H.H., Royer, G.P. (eds) Enzyme Engineering. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3749-2_3
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DOI: https://doi.org/10.1007/978-1-4684-3749-2_3
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