Advertisement

Novel Enzymes from Methylotrophic Microorganisms

  • Allen I. Laskin
  • Ching T. Hou
  • Ramesh N. Patel

Abstract

In the course of our studies on methylotrophs, microorganisms that grow on methane and on other C1 compounds, we discovered that cell suspensions of methane-grown bacteria have the ability to oxidize gaseous 1-alkenes to their corresponding 1,2-epoxyalkanes, as well as to hydroxylate not only methane, but also the other gaseous alkanes (1). Thus, ethylene, propylene, 1-butene, and butadiene are converted to expodies, and methand, ethane, propane, and butane are hydroxylated; both primary and secondary alcohol products were detected. The product epoxides are not further metabolized and they accumulate extracellularly.

Keywords

Secondary Alcohol Tertiary Alcohol Methane Monooxygenase Methylotrophic Bacterium Gaseous Alkane 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    HOU, C.T., PATEL, R., LASKIN, A.I., & BARNABE, N. Appl. Environ. Microbiol. 38; 127, 1979.Google Scholar
  2. 2.
    PATEL, R.N., HOU, C.T., LASKIN, A.I., FELIX, A., & DERELANKO, P. J. Bacteriol. 139: 675, 1979.Google Scholar
  3. 3.
    COLBY, J., STIRLING, D.I., & DALTON, H. Biochem. J. 165: 395, 1977.Google Scholar
  4. 4.
    STIRLING, D.I., COLBY, J., & DALTON, H. Biochem. J. 177: 361, 1979.Google Scholar
  5. 5.
    STIRLING, D.I. & DALTON, H. FEMS Microbiol. Lett. 5: 315, 1979.CrossRefGoogle Scholar
  6. 6.
    HIGGINS, I.J., HAMMOND, R.C., SARIASLANI, D.B., DAVIES, M.M., TRYHORN, S.E., & TAYLOR, F. Biochem. Biophys. Res. Commun. 89: 671, 1979.CrossRefGoogle Scholar
  7. 7.
    HOU, C.T., PATEL, R.N., LASKIN, A.I., BARNABE, N. & MARCZAK, I., FEBS Lett. 101: 179, 1979.CrossRefGoogle Scholar
  8. 8.
    HOU, C.T., PATEL, R., LASKIN, A.I., BARNABE, N. & MARCZAK, I. Appl. Environ. Microbiol. 38: 135, 1979.Google Scholar
  9. 9.
    PATEL, R.N., HOU, C.T., LASKIN, A.I., DERELANKO, P. & FELIX, A. Appl. Environ. Microbiol. 38: 219, 1979.Google Scholar
  10. 10.
    PATEL, R.N., HOU, C.T., LASKIN, A.I., DERELANKO, P. Y FELIX, A. (in press).Google Scholar

Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • Allen I. Laskin
    • 1
  • Ching T. Hou
    • 1
  • Ramesh N. Patel
    • 1
  1. 1.Exxon Research and Engineering CompanyLindenUSA

Personalised recommendations