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A New Enzyme Transducer Combination: The Enzyme Transistor

  • B. Danielsson
  • K. Mosbach
  • I. Lundstrom
  • L. Stilbert

Abstract

The p-channel Pd-MOS-transistor used resembles an ordinary field-effect transistor, but the gate metal is a catalytic metal, palladium, instead of e.g. aluminum, which makes it sensitive to hydrogen (1). It has also been found to respond to other hydrogen containing gases such as NH3 (1) and H2S (2). The practical sensitivity of the device is better than 1 ppm of hydrogen or 10 ppm of NH3 in air. As a number of enzymic reactions produce these gases we investigated the analytical potential of a combination of such a specific transistor with enzymes.

Keywords

Threshold Voltage Hydrogen Concentration Urease Activity Catalytic Metal Gate Metal 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Lundstrom, K.I., Shivaraman, M.S. & Svensson, C.M. J. Appl. Phys.47: 3876–3881, 1975.CrossRefGoogle Scholar
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    Shivaraman, M.S. J. Appl. Phys. 47: 3592–3595, 1976.Google Scholar
  3. 3.
    Danielsson, B., Lundstrom, I., Mosbach, K. & Stiblert, L. Anal. Lett.12: No. B11, 1979, in press.Google Scholar
  4. 4.
    Danielsson, B., Mattiasson, B. & Mosbach, K. Pure & Appl. Chem.51: 1443–1457, 1979.CrossRefGoogle Scholar
  5. 5.
    Schneider, K. & Schlegel, H.G. Biochim. Biophys.452: 66–80, 1976.Google Scholar

Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • B. Danielsson
    • 1
  • K. Mosbach
    • 1
  • I. Lundstrom
    • 2
  • L. Stilbert
    • 3
  1. 1.Chemical centerUniversity of LundLundSweden
  2. 2.Applied PhysicsLikoping Institute of TechnologySweden
  3. 3.Research Lab. ElectronicsChalmers University of TechnologyGothenburgSweden

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