Rheology pp 567-572 | Cite as

An Optical Method for Studying Red Blood Cells Orientation and Aggregation in a Couette Flow of Blood Suspension

  • P. Mills
  • D. Quemada
  • J. Dufaux


Red blood cell aggregation is certainly the most important factor in the non newtonian behaviour of normal human blood. Aggregated red blood cells build up rouleaux; this aggregation is reversible: at rest, the rouleaux form a three dimensional network structure; when a finite stress is applied to the suspension the structure breaks. Increasing the stress, the rouleaux are gradually disrupted and are finally reduced up to individual cells. With decrease in stress individual cells build up again rouleaux. In a steady state a dynamical equilibrium exists between the size of rouleaux and the stress applied. When the applied stress is high enough to break the rouleaux, cells can be oriented and deformed in the flow. There was studied an experimental method which allows us to rely the luminous flux backscattered by rouleaux and individual cells to their mean size and to their orientation.


Shear Rate COUETTE Flow Luminous Flux Normal Human Blood Shear Rate Stress 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    MILLS P., et al. Submitted to Revue de Physique Appliquée Paris.Google Scholar
  2. 2.
    KLOSE H.T. and al. Pflügers Arch. 333, 126–139 (1972).CrossRefGoogle Scholar
  3. 3.
    HEALY J.C., These, Univ.Paris VI, PARIS (1973)Google Scholar
  4. 4.
    MILLS P. etal.“Hemorheology and diseases” 17–19 Nov 1979, Nancy, Douin Paris (In Press).Google Scholar
  5. 5.
    CHIEN S. et al.Biorheology vol 8,35–57 (1971).Google Scholar
  6. 6.
    MILLS P. et al.3rd Int.Conf.on Physico-Chemical Hydrodynamics Madrid March 30-April 2 (1980).Google Scholar
  7. 7.
    LERCHE D. et al.8thlnt.Cong.on Rheology 1–6 Sept.(1980).Google Scholar

Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • P. Mills
    • 1
  • D. Quemada
    • 1
  • J. Dufaux
    • 1
  1. 1.Laboratoire de BiorhéologieUniversité Paris VIIParisFrance

Personalised recommendations