An Optical Method for Studying Red Blood Cells Orientation and Aggregation in a Couette Flow of Blood Suspension
Red blood cell aggregation is certainly the most important factor in the non newtonian behaviour of normal human blood. Aggregated red blood cells build up rouleaux; this aggregation is reversible: at rest, the rouleaux form a three dimensional network structure; when a finite stress is applied to the suspension the structure breaks. Increasing the stress, the rouleaux are gradually disrupted and are finally reduced up to individual cells. With decrease in stress individual cells build up again rouleaux. In a steady state a dynamical equilibrium exists between the size of rouleaux and the stress applied. When the applied stress is high enough to break the rouleaux, cells can be oriented and deformed in the flow. There was studied an experimental method which allows us to rely the luminous flux backscattered by rouleaux and individual cells to their mean size and to their orientation.
KeywordsShear Rate COUETTE Flow Luminous Flux Normal Human Blood Shear Rate Stress
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