Rheology pp 521-526 | Cite as

Effects of Membrane Anisotropy Upon the Viscoelasticity of Spherical Cell Suspensions

  • Akio Sakanishi
  • Yo Takano


In order to develop and to apply the method how the information about the mechanical property of biological cells including red blood cells is attained from measurements of cell suspensions, we have studied both theoretical and experimental.1 Theoretically the homogeneous and isotropic system has been treated in calculation of bulk modulus,2 shear viscosity3 and rigidity4 in spherical shell structure suspensions. However in biological cells the cellular membrane has a quite peculiar anisotropy: the translational diffusion constant of lipid molecule is in the order of 10−8 cm2 sec−1 within the membrane surface for instance while it is in the rough order of 10−15 cm2 sec−1 in the direction perpendicular to the membrane. In this paper the bulk modulus and the shear rigidity are calculated in spherical cell suspension taking into consideration of membrane anisotropy.


Bulk Modulus Lipid Molecule Biological Cell Spherical Cell Elastic Membrane 
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  1. 1.
    A. Sakanishi, S. Mitaku and Y. Takano, Linear viscoelasticity of suspensions of spherical shell structures and erythrocyte membrane, Thrombosis Research Suppl. II 8: 35 (1976).CrossRefGoogle Scholar
  2. 2.
    A. Sakanishi and Y. Takano, Bulk modulus of the disperse system of spherical cells with compressible and elastic membrane, J. Phys. Soc. Japan 32: 1160 (1972).ADSCrossRefGoogle Scholar
  3. 3.
    A. Sakanishi and Y. Takano, Complex viscosity of dispersions of spherical cells with elastic membrane, Japan J. Appl. Phys. 13: 882 (1974).CrossRefGoogle Scholar
  4. 4.
    Y. Takano and A. Sakanishi, Complex rigidity of dispersions of spherical shell structures with material compressibility, J. Appl. Phys. 44:4023 (1973); ibid. 45: 2811 (1974).Google Scholar

Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • Akio Sakanishi
    • 2
  • Yo Takano
    • 1
  1. 1.Department of ChemistryUniversity of WisconsinMadisonUSA
  2. 2.Department of Physics, Faculty of General StudiesGunma UniversityMaebashiJapan

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