Aging of Hepatocytes

  • Akihiro Shima
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 129)


The purpose of this paper is not to survey current knowledge on aging of hepatic cells in general, but to summarize some of our own results that are concerned with the age changes in DNA content-based polyploidization of hepatocytes of three kinds of laboratory animals: mouse (1), fish (2), and house shrew (3).


Tritiated Thymidine Mouse Hepatocyte Maximum Life Span Hepatocyte Nucleus Oryzias Latipes 
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Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • Akihiro Shima
    • 1
  1. 1.Department of Experimental RadiologyShiga University of Medical ScienceŌtsu, Shiga 520-21Japan

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