Aging of Hepatocytes
The purpose of this paper is not to survey current knowledge on aging of hepatic cells in general, but to summarize some of our own results that are concerned with the age changes in DNA content-based polyploidization of hepatocytes of three kinds of laboratory animals: mouse (1), fish (2), and house shrew (3).
KeywordsParaffin Thymidine Kelly dNTP Pararosaniline
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- 3.A. Shima, S. Shinohara, and K. Kondo, Unpublished data.Google Scholar
- 7.H. Tauchi, On the fundamental morphology of the senile changes, Nagoya J. Med. Sci. 24:97 (1960).Google Scholar
- 10.A. Shima, N. Egami, and T. Sugahara, Comparative study on the polyploidization of hepatocytes of mouse and fish during ageing, in:“Liver and Aging-1978,” K. Kitani, ed., Elsevier/ North-Holland Biomedical Press, Amsterdam (1978).Google Scholar
- 15.M. Matsui, A. Shima, and N. Egami, Autoradiographic detection of the template-primer activities of DNA by exogenous DNA polymerases in fixed mouse tissues, J. Fac. Sci., Univ. Tokyo, Sec. IV, 13:399 (1976).Google Scholar
- 19.Y. Hyodo-Taguchi and N. Egami, Development of gastrointestinal radiation injury and recovery at different temperatures in fish, in:“Comparative Cellular and Species Radiosensitivity,” V. P. Bond and T. Sugahara, eds., Igaku-Shoin, Tokyo (1969).Google Scholar
- 21.K. Kondo, S. Oda, H. Takahashi, and R. Izeki, The house shrew: A new laboratory animal for comparative study of aging, in:“Abstracts for Plenary Sessions and Symposia of the XIth International Congress of Gerontology,” Tokyo (1978).Google Scholar