Liposomes as Macromolecular Carriers for the Introduction of RNA and DNA into Cells

  • D. Papahadjopoulos
  • T. Wilson
  • R. Taber
Part of the NATO Advanced Study Institutes Series book series (NSSA, volume 31)


Liposomes are vesicles composed of one or more lipid bilayers completely surrounding an internal aqueous space. They are usually composed of phospholipids either in pure form or in combination with other amphipathic molecules such as sterols, long chain bases or acids. The structure of liposomes varies from large (0.5 to 5μ) multilamellar vesicles (1) to small (~300Å) unilamellar vesicles (2, 3) or to unilamellar vesicles of intermediate size (4–6).


Lipid Vesicle Effective Delivery Phospholipid Vesicle Multilamellar Vesicle Specific Infectivity 
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Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • D. Papahadjopoulos
    • 1
  • T. Wilson
    • 2
  • R. Taber
    • 3
  1. 1.Cancer Research InstituteUC San Francisco Medical CenterSan FranciscoUSA
  2. 2.Department of Physiology and BiophysicsCMDNJ-Rutgers Medical SchoolPiscatawayUSA
  3. 3.Department of Viral Oncology and Experimental PathologyRoswell Park Memorial InstituteBuffaloUSA

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